ReviewWorld journal of clinical oncology2016
Overview, prevention and management of chemotherapy extravasation.
Review in World journal of clinical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 3 syntheses or guidelines pooled it, 188 citations in OpenAlex.
- ONS/ASCO Guideline on the Management of Antineoplastic Extravasation.Clinical journal of oncology nursing · 2025Guideline
- Adult oncology patients' experiences of living with a central venous catheter: a systematic review and meta-synthesis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Pooled it
- ECO-SEOM-SEEO safety recommendations guideline for cancer patients receiving intravenous therapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020Guideline
- Management of extravasations of enfortumab vedotin and pembrolizumab: a case report and mini review of the current literature.Journal of cancer research and clinical oncology · 2026Review
- "Extravasation injuries requiring plastic surgery - a retrospective single center study".JPRAS open · 2026Article
- Design and Protocol of a Randomised Controlled Trial Evaluating Virtual Reality to Improve Patient Experience During PICC and PICC-PORT Placement in Oncology Patients.Nursing reports (Pavia, Italy) · 2026Article
- Supportive care challenges in a resource limited oncology setting: prevalence and management of anthracycline and vinca alkaloid extravasation in Sudan.BMC cancer · 2026Article
- Effect of digital chemotherapy extravasation education based on Orem's self-care theory in cancer patients: A quasi-experimental study.PloS one · 2026Article
- Clinical guidelines for the management of cytostatic extravasation in children.Contemporary oncology (Poznan, Poland) · 2026Review
- Educational technologies for the prevention and management of extravasation of antineoplastic agents: an integrative review.Revista brasileira de enfermagem · 2026Review
- Targeted Nanocomplex Delivery for Protecting Vascular Integrity and Enhancing Anticancer Effects in Hepatocellular Carcinoma.Small science · 2026Article
- When to remove implantable vascular access ports? a retrospective analysis of 376 patients with breast cancer and implantable vascular access ports.BMC surgery · 2025Article
- Extravascular leakage of dexrazoxane that occurred in a patient with diffuse large B-cell lymphoma: a case report.Journal of pharmaceutical health care and sciences · 2025Article
- Extravasation of Intravenous Acyclovir in a Patient With Human Herpesvirus 7 Encephalitis: A Case Report.Cureus · 2025Article
- Case Report: A successful multidisciplinary approach to doxorubicin extravasation from a PICC-port in a patient with breast cancer.Frontiers in oncology · 2025Article
- Exploring Extravasation in Cancer Patients.Cancers · 2024Review
- Desquamative extravasation reaction secondary to enfortumab vedotin.JAAD case reports · 2024Article
- Safe practices for prevention and management of antineoplastic agent extravasation: development of an educational video.Revista brasileira de enfermagem · 2024Article
- Management of Epirubicin Extravasation Injuries of the Hand with Debridement and Flap Cover-A Case Series.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2023Article
- Drug extravasation with Enfortumab vedotin.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2023Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chemotherapy extravasation remains an accidental complication of chemotherapy administration and may result in serious damage to patients. We review in this article the clinical aspects of chemotherapy extravasation and latest advances in definitions, classification, prevention, management and guidelines. We review the grading of extravasation and tissue damage according to various chemotherapeutic drugs and present an update on treatment and new antidotes including dexrazoxane for anthracyclines extravasation. We highlight the importance of education and training of the oncology team for prevention and prompt pharmacological and non-pharmacological management and stress the availability of new antidotes like dexrazoxane wherever anthracyclines are being infused.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.