Evidence map›Paper›PMID 26862368›Full record

ArticleWorld journal of gastrointestinal endoscopy2016

Safety of immediate endoscopic sphincterotomy in acute suppurative cholangitis caused by choledocholithiasis.

Tomoyasu Ito, Jin Kan Sai, Hironao Okubo, Hiroaki Saito, Shigeto Ishii, Ryo Kanazawa, Ko Tomishima, Sumio Watanabe, Shuichiro Shiina

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastrointestinal endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Tomoyasu ItoTomoyasu Ito, Jin Kan Sai, Hiroaki Saito, Shigeto Ishii, Ryo Kanazawa, Ko Tomishima, Sumio Watanabe, Shuichiro Shiina, Department of Gastroenterology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
Jin Kan SaiTomoyasu Ito, Jin Kan Sai, Hiroaki Saito, Shigeto Ishii, Ryo Kanazawa, Ko Tomishima, Sumio Watanabe, Shuichiro Shiina, Department of Gastroenterology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
Hironao OkuboTomoyasu Ito, Jin Kan Sai, Hiroaki Saito, Shigeto Ishii, Ryo Kanazawa, Ko Tomishima, Sumio Watanabe, Shuichiro Shiina, Department of Gastroenterology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
Hiroaki SaitoTomoyasu Ito, Jin Kan Sai, Hiroaki Saito, Shigeto Ishii, Ryo Kanazawa, Ko Tomishima, Sumio Watanabe, Shuichiro Shiina, Department of Gastroenterology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
Shigeto IshiiTomoyasu Ito, Jin Kan Sai, Hiroaki Saito, Shigeto Ishii, Ryo Kanazawa, Ko Tomishima, Sumio Watanabe, Shuichiro Shiina, Department of Gastroenterology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
Ryo KanazawaTomoyasu Ito, Jin Kan Sai, Hiroaki Saito, Shigeto Ishii, Ryo Kanazawa, Ko Tomishima, Sumio Watanabe, Shuichiro Shiina, Department of Gastroenterology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
Ko TomishimaTomoyasu Ito, Jin Kan Sai, Hiroaki Saito, Shigeto Ishii, Ryo Kanazawa, Ko Tomishima, Sumio Watanabe, Shuichiro Shiina, Department of Gastroenterology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
Sumio WatanabeTomoyasu Ito, Jin Kan Sai, Hiroaki Saito, Shigeto Ishii, Ryo Kanazawa, Ko Tomishima, Sumio Watanabe, Shuichiro Shiina, Department of Gastroenterology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
Shuichiro ShiinaTomoyasu Ito, Jin Kan Sai, Hiroaki Saito, Shigeto Ishii, Ryo Kanazawa, Ko Tomishima, Sumio Watanabe, Shuichiro Shiina, Department of Gastroenterology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
Creative Research Enterprises (United States) · USJuntendo University Nerima Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo examine the safety of immediate endoscopic sphincterotomy (EST) in patients with acute suppurative cholangitis (ASC) caused by choledocholithiasis, as compared with elective EST.

methodsPatients with ASC due to choledocholithiasis were allocated to two groups: Those who underwent EST immediately and those who underwent EBD followed by EST 1 wk later because they were under anticoagulant therapy, had a coagulopathy (international normalized ratio > 1.3, partial thromboplastin time greater than twice that of control), or had a platelet count < 50000 × 10(3)/μL. One of four trainees [200-400 cases of endoscopic retrograde cholangiopancreatography (ERCP)] supervised by a specialist (> 10000 cases of ERCP) performed the procedures. The success and complication rates associated with EST in each group were examined.

resultsOf the 87 patients with ASC, 59 were in the immediate EST group and 28 in the elective EST group. EST was successful in all patients in both groups. There were no complications associated with EST in either group of patients, although white blood cell count, C-reactive protein, total bilirubin, and serum concentrations of liver enzymes just before EST were significantly higher in the immediate EST group than in the elective EST group.

conclusionImmediate EST can be as safe as elective EST for patients with ASC associated with choledocholithiasis provided they are not under anticoagulant therapy, or do not have a coagulopathy or a platelet count < 50000 × 10(3)/μL. Moreover, the procedure was safely performed by a trainee under the supervision of an experienced specialist.

Indexed as

Acute cholangitisComplicationsEndoscopic sphincterotomy

Identifiers

PMID26862368
PMCPMC4734977
OpenAlexW2262626167

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.