Evidence map›Paper›PMID 26862233›Full record

ArticlePublic health reports (Washington, D.C. : 1974)

Scaling Up HIV Testing in an Academic Emergency Department: An Integrated Testing Model with Rapid Fourth-Generation and Point-of-Care Testing.

Danielle Signer, Stephen Peterson, Yu-Hsiang Hsieh, Somiya Haider, Mustapha Saheed, Paula Neira, Cassie Wicken, Richard E Rothman

Abstract read
In one paragraph

Article in Public health reports (Washington, D.C. : 1974). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Observational
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  12. Expanding Hospital Human Immunodeficiency Virus Testing in the Bronx, New York and Washington, District of Columbia: Results From the HPTN 065 Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
  13. Review
  14. Lessons Learned From the Development and Parameterization of a Computer Simulation Model to Evaluate Task Modification for Health Care Providers.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2018
    Article
  15. Article
  16. Real-world performance of the new US HIV testing algorithm in medical settings.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2017
    Article
  17. Article
  18. Evaluation of the Utility of Point-of-Care HIV Testing on a Canadian Internal Medicine Inpatient Unit.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Danielle SignerJohns Hopkins University, Department of Emergency Medicine, Baltimore, MD.
Stephen PetersonJohns Hopkins University, Department of Emergency Medicine, Baltimore, MD.
Yu-Hsiang HsiehJohns Hopkins University, Department of Emergency Medicine, Baltimore, MD.
Somiya HaiderJohns Hopkins University, Department of Emergency Medicine, Baltimore, MD.
Mustapha SaheedJohns Hopkins University, Department of Emergency Medicine, Baltimore, MD.
Paula NeiraJohns Hopkins University, Department of Emergency Medicine, Baltimore, MD.
Cassie WickenJohns Hopkins University, Department of Emergency Medicine, Baltimore, MD.
Richard E RothmanJohns Hopkins University, Department of Emergency Medicine, Baltimore, MD; Johns Hopkins University, Department of Medicine, Division of Infectious Diseases, Baltimore, MD.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe evaluated two approaches for implementing routine HIV screening in an inner-city, academic emergency department (ED). These approaches differed by staffing model and type of HIV testing technology used. The programmatic outcomes assessed included the total number of tests performed, proportion of newly identified HIV-positive patients, and proportion of newly diagnosed individuals who were linked to care.

methodsThis study examined specific outcomes for two distinct, successive approaches to implementing HIV screening in an inner-city, academic ED, from July 2012 through June 2013 (Program One), and from August 2013 through July 2014 (Program Two). Program One used a supplementary staff-only HIV testing model with point-of-care (POC) oral testing. Program Two used a triage-integrated, nurse-driven HIV testing model with fourth-generation blood and POC testing, and an expedited linkage-to-care process.

resultsDuring Program One, 6,832 eligible patients were tested for HIV with a rapid POC oral HIV test. Sixteen patients (0.2%) were newly diagnosed with HIV, of whom 13 were successfully linked to care. During Program Two, 8,233 eligible patients were tested for HIV, of whom 3,124 (38.0%) received a blood test and 5,109 (62.0%) received a rapid POC test. Of all patients tested in Program Two, 29 (0.4%) were newly diagnosed with HIV, four of whom had acute infections and 27 of whom were successfully linked to care. We found a statistically significant difference in the proportion of the eligible population tested-8,233 of 49,697 (16.6%) in Program Two and 6,832 of 46,818 (14.6%) in Program One. These differences from Program One to Program Two corresponded to increases in testing volume (n=1,401 tests), number of patients newly diagnosed with HIV (n=13), and proportion of patients successfully linked to care (from 81.0% to 93.0%).

conclusionIntegrating HIV screening into the standard triage workflow resulted in a higher proportion of ED patients being tested for HIV as compared with the supplementary staff-only HIV testing model. New rapid fourth-generation testing technology allowed the identification of acute HIV infection and same-visit confirmation of a positive diagnosis.

Indexed as

Academic Medical CentersAdolescentAdultAgedAIDS SerodiagnosisEmergency Service, HospitalFemaleHumansMaleMiddle AgedModels, OrganizationalPoint-of-Care SystemsYoung Adult

Identifiers

PMID26862233
PMCPMC4720609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.