ArticleLasers in medical science2016
Minimally invasive, non-ablative Er:YAG laser treatment of stress urinary incontinence in women--a pilot study.
Article in Lasers in medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 49 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Trial Comparing the Use of Laser and of Kinesiotherapy for the Treatment of Female Stress Urinary Incontinence - a Pilot Study
Monocentric, Prospective Pilot Study to Test the Efficacy and Safety of the FotonaSmooth Erbium:YAG Laser for the Treatment of Urethral Pain Syndrome in Women
Who cites it
49 citing papers in PubMed, 4 syntheses or guidelines pooled it, 136 citations in OpenAlex.
- The use of vaginal lasers in the treatment of urinary incontinence and overactive bladder, systematic review.International urogynecology journal · 2021Pooled it
- Effects of non-ablative Er:YAG laser on the skin and the vaginal wall: systematic review of the clinical and experimental literature.International urogynecology journal · 2020Pooled it
- The Clinical Role of LASER for Vulvar and Vaginal Treatments in Gynecology and Female Urology: An ICS/ISSVD Best Practice Consensus Document.Journal of lower genital tract disease · 2019Pooled it
- A systematic review on vaginal laser therapy for treating stress urinary incontinence: Do we have enough evidence?International urogynecology journal · 2017Pooled it
- Vaginal Erbium Laser for the Treatment of Mild-to-Moderate Stress Urinary Incontinence: A Multicentre Randomised Sham-Controlled Trial.BJOG : an international journal of obstetrics and gynaecology · 2026Trial
- Vaginal Erbium Laser Versus Pelvic Floor Muscle Training for Stress Urinary Incontinence: A Randomised Controlled Trial.International urogynecology journal · 2025Trial
- Efficacy and safety of non-ablative ErYAG laser for mild to moderate stress urinary incontinence: a prospective, multicenter, randomized, sham-controlled clinical trial.Lasers in medical science · 2025Trial
- Vaginal erbium laser for treatment of stress urinary incontinence: optimization of treatment regimen for a sustained long-term effect.Lasers in medical science · 2022Trial
- The efficacy of erbium-doped yttrium aluminum garnet (Er:YAG) laser in the treatment of decreased sexual sensation: a randomized, placebo-controlled trial.Lasers in medical science · 2022Trial
- Prospective trial of a 2940 nm Er:YAG laser for the treatment of meibomian gland dysfunction.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Trial
- Intraurethral Erbium:YAG laser for the management of urinary symptoms of genitourinary syndrome of menopause: A pilot study.Lasers in surgery and medicine · 2018Trial
- Non-ablative erbium YAG laser for the treatment of type III stress urinary incontinence (intrinsic sphincter deficiency).Lasers in medical science · 2017Trial
- Intra-Oral Lasering for the Treatment of Nasolabial Folds, Marionette Lines, and Jowls: Case Examples and Protocol Methodology.Journal of cosmetic dermatology · 2026Article
- Non-ablative transurethral laser treatment for collagen remodeling with functional recovery in an in vivo model of stress urinary incontinence.Scientific reports · 2026Article
- Combined intraurethral and intravaginal er: YAG laser (UEL + VEL) therapy vs. intraurethral (UEL) alone treatment for stress urinary incontinence? a multicenter retrospective cohort study, real world data from the VELA centers.Lasers in medical science · 2025Article
- The Effect of Vaginal Er:YAG Laser Therapy on Pelvic Floor Symptoms in Women With Stress Urinary Incontinence: A Single-Center Cohort Study.Lasers in surgery and medicine · 2025Article
- A new approach to treatment of stress urinary incontinence using non-ablative transurethral laser.Scientific reports · 2025Article
- Synergistic Effects of Thread Lifting, Autologous Fat Grafting, and Multi-Modal Laser Therapy in Facial Rejuvenation.Aesthetic surgery journal. Open forum · 2025Article
- The Impact of IncontiLase Er:YAG Laser Treatment on the Quality of Life of Women With Stress Urinary Incontinence.Advances in urology · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study presents an assessment of mechanism of action and a pilot clinical study of efficacy and safety of the Er:YAG laser for the treatment of stress urinary incontinence (SUI). The subject of this study is a treatment of SUI with a 2940 nm Er:YAG laser, operating in a special SMOOTH mode designed to increase temperature of the vaginal mucosa up to maximally 60-65 °C without ablating the epidermis. Numerical modelling of the temperature distribution within mucosa tissue following an irradiation with the SMOOTH mode Er:YAG laser was performed in order to determine the appropriate range of laser parameters. The laser treatment parameters were further confirmed by measuring in vivo temperatures of the vaginal mucosa using a thermal camera. To investigate the clinical efficacy and safety of the SMOOTH mode Er:YAG laser SUI treatment, a pilot clinical study was performed. The study recruited 31 female patients suffering from SUI. Follow-ups were scheduled at 1, 2, and 6 months post treatment. ICIQ-UI questionnaires were collected as a primary trial endpoint. Secondary endpoints included perineometry and residual urine volume measurements at baseline and all follow-ups. Thermal camera measurements have shown the optimal increase in temperature of the vaginal mucosa following treatment of SUI with a SMOOTH mode Er:YAG laser. Primary endpoint, the change in ICIQ-UI score, showed clinically relevant and statistically significant improvement after all follow-ups compared to baseline scores. There was also improvement in the secondary endpoints. Only mild and transient adverse events and no serious adverse events were reported. The results indicate that non-ablative Er:YAG laser therapy is a promising minimally invasive non-surgical option for treating women with SUI symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.