ArticleLasers in medical science2016
The effect of low-level laser therapy on oxidative stress and functional fitness in aged rats subjected to swimming: an aerobic exercise.
Article in Lasers in medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Effects of Photobiomodulation Therapy on Oxidative Stress in Muscle Injury Animal Models: A Systematic Review.Oxidative medicine and cellular longevity · 2017Pooled it
- Quadriceps femoris performance after resistance training with and without photobiomodulation in elderly women: a randomized clinical trial.Lasers in medical science · 2019Trial
- Low-level laser therapy (LLLT) does not reduce subcutaneous adipose tissue by local adipocyte injury but rather by modulation of systemic lipid metabolism.Lasers in medical science · 2017Trial
- Modulating depressive-like behaviors, memory impairment, and oxidative stress in chronic stress rat model using visible light therapy.Scientific reports · 2025Article
- Photobiomodulation therapy reverses spermatogenesis arrest in hyperthermia-induced azoospermia mouse model.Lasers in medical science · 2023Article
- Photobiomodulation in 3D tissue engineering.Journal of biomedical optics · 2022Article
- Photobiomodulation intervention improves oxidative, inflammatory, and morphological parameters of skeletal muscle in cirrhotic Wistar rats.Lasers in medical science · 2022Article
- Oxidative Stress and Abnormal Tendon Sonographic Features in Elite Soccer Players (A Pilot Study).Revista brasileira de ortopedia · 2021Article
- Post-resistance exercise photobiomodulation therapy has a more effective antioxidant effect than pre-application on muscle oxidative stress.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2021Article
- Low-Level Laser Effect on Peripheral Sciatic Regeneration Under the Systemic Inflammatory Condition of Periodontal Disease.Journal of lasers in medical sciences · 2020Article
- Effects of Endurance Running Training Associated With Photobiomodulation on 5-Km Performance and Muscle Soreness: A Randomized Placebo-Controlled Trial.Frontiers in physiology · 2019Article
- Effect of photobiomodulation therapy on oxidative stress markers of gastrocnemius muscle of diabetic rats subjected to high-intensity exercise.Lasers in medical science · 2018Article
- Mechanisms and Mitochondrial Redox Signaling in Photobiomodulation.Photochemistry and photobiology · 2018Review
- Effect of Low-Level Laser Irradiation on the Function of Glycated Catalase.Journal of lasers in medical sciences · 2018Article
- Photobiomodulation Leads to Reduced Oxidative Stress in Rats Submitted to High-Intensity Resistive Exercise.Oxidative medicine and cellular longevity · 2018Article
- The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways.Redox biology · 2017Article
- Photobiomodulation therapy associated with treadmill training in the oxidative stress in a collagen-induced arthritis model.Lasers in medical science · 2017Article
- Proanthocyanidins Attenuation of HBioMed research international · 2017Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the present study was to determine whether low-level laser therapy (LLLT) in conjunction with aerobic training interferes with oxidative stress, thereby influencing the performance of old rats participating in swimming. Thirty Wistar rats (Norvegicus albinus) (24 aged and six young) were tested. The older animals were randomly divided into aged-control, aged-exercise, aged-LLLT, aged-LLLT/exercise, and young-control. Aerobic capacity (VO2max(0.75)) was analyzed before and after the training period. The exercise groups were trained for 6 weeks, and the LLLT was applied at 808 nm and 4 J energy. The rats were euthanized, and muscle tissue was collected to analyze the index of lipid peroxidation thiobarbituric acid reactive substances (TBARS), glutathione (GSH), superoxide dismutase (SOD), and catalase (CAT) activities. VO2 (0.75)max values in the aged-LLLT/exercise group were significantly higher from those in the baseline older group (p <0.01) and the LLLT and exercise group (p <0.05). The results indicate that the activities of CAT, SOD, and GPx were higher and statistically significant (p <0.05) in the LLLT/exercise group than those in the LLLT and exercise groups. Young animals presented lesser and statistically significant activities of antioxidant enzymes compared to the aged group. The LLLT/exercise group and the LLLT and exercise group could also mitigate the concentration of TBARS (p > 0.05). Laser therapy in conjunction with aerobic training may reduce oxidative stress, as well as increase VO2 (0.75)max, indicating that an aerobic exercise such as swimming increases speed and improves performance in aged animals treated with LLLT.
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