ArticleJournal of autism and developmental disorders2016
Change in the Behavioral Phenotype of Adolescents and Adults with FXS: Role of the Family Environment.
Article in Journal of autism and developmental disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Social determinants associated with mental health problems in youth with intellectual disability: a systematic literature review.European child & adolescent psychiatry · 2025Pooled it
- Pooled it
- Autism spectrum disorder in females with fragile X syndrome: a systematic review and meta-analysis of prevalence.Journal of neurodevelopmental disorders · 2021Pooled it
- Broad perspective on socio-economic disadvantages in youth with mild to borderline intellectual disabilities in mental health care.European child & adolescent psychiatry · 2026Article
- FMR1 Premutation Carrier Mothers' Daily Negative Affect and Cortisol: Probing the Impacts of Stress Exposure, Coping Style, and CGG Repeats.American journal on intellectual and developmental disabilities · 2025Article
- Impact of the Great Recession on Adults With Autism and Their Mothers.American journal on intellectual and developmental disabilities · 2024Article
- Reliability of resting-state electrophysiology in fragile X syndrome.Biomarkers in neuropsychiatry · 2023Article
- Change in Behavior Problems from Childhood Through Adolescence for Children with Fragile X Syndrome.Journal of autism and developmental disorders · 2022Article
- Parental stress and adjustment in the context of rare genetic syndromes: A scoping review.Journal of intellectual disabilities : JOID · 2022Article
- Verbal Ability, Behavior Problems, and Mother-Child Relationship Quality in Autism Spectrum Disorder.Journal of autism and developmental disorders · 2022Article
- Change in Maladaptive Behavior Affects Intergenerational Relationships in Fragile X Syndrome.American journal on intellectual and developmental disabilities · 2022Article
- Trajectories of Change in the Behavioral and Health Phenotype of Adolescents and Adults with Fragile X Syndrome and Intellectual Disability: Longitudinal Trends Over a Decade.Journal of autism and developmental disorders · 2020Article
- Inhibition deficits are modulated by age and CGG repeat length in carriers of the FMR1 premutation allele who are mothers of children with fragile X syndrome.Brain and cognition · 2020Article
- Unaffected siblings of adolescents and adults with fragile X syndrome: Effects on maternal well-being.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2019Article
- Friendships and social participation as markers of quality of life of adolescents and adults with fragile X syndrome and autism.Autism : the international journal of research and practice · 2019Article
- Health Profiles of Mosaic Versus Non-mosaicFrontiers in genetics · 2018Article
- Of Men and Mice: Modeling the Fragile X Syndrome.Frontiers in molecular neuroscience · 2018Article
- The Future of Fragile X Syndrome: CDC Stakeholder Meeting Summary.Pediatrics · 2017Article
- Updated report on tools to measure outcomes of clinical trials in fragile X syndrome.Journal of neurodevelopmental disorders · 2017Review
- Distance delivery of a parent-implemented language intervention for young boys with fragile X syndrome.Autism & developmental language impairmentsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The present study examined trajectories of adaptive behavior, behavior problems, psychological symptoms, and autism symptoms in adolescents and adults with fragile X syndrome (n = 147) over a three-year period. Adaptive behavior significantly increased over time, particularly for adolescents, and the severity of behavior problems decreased over time. Family environmental factors predicted phenotypic variables net of gender, intellectual disability status, and medication use. Maternal warmth was associated with higher levels of adaptive behavior, lower levels of autism symptoms, and decreases in behavior problems over time. Maternal depressive symptoms and criticism were associated with higher levels of psychological symptoms. Implications for interventions are discussed.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.