ArticleCritical care (London, England)2016
A guide to human in vivo microcirculatory flow image analysis.
Article in Critical care (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06253325 (An Observational Pilot Study for the Multi-Modality Risk Prediction and Early Identification of Critically Ill Septic Patients in the Emergency Department), which is not on this map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Observational Pilot Study for the Multi-Modality Risk Prediction and Early Identification of Critically Ill Septic Patients in the Emergency Department
Who cites it
60 citing papers in PubMed.
- Trial
- Microcirculatory perfusion disturbances in septic shock: results from the ProCESS trial.Critical care (London, England) · 2018Trial
- Evaluating the endothelial glycocalyx from bench to bedside: a translational framework for microvascular assessment.Angiogenesis · 2026Review
- Microcirculation and Cerebrovascular Autoregulation in Patients With Mechanical Circulatory Support Devices.Journal of stroke · 2026Review
- Improved Detection of Capillaries in High-Resolution Handheld Vital Microscopy by Use of the MicroTools Advanced Computer Vision Algorithm.Microcirculation (New York, N.Y. : 1994) · 2026Article
- Reproducibility of glycocheck measurements in patients under general anesthesia with muscle relaxants: A prospective observational study.Journal of clinical monitoring and computing · 2025Observational
- Visualizing hemodynamics: innovative graphical displays and imaging techniques in anesthesia and critical care.Critical care (London, England) · 2025Review
- Glycosaminoglycans: Participants in Microvascular Coagulation of Sepsis.Thrombosis and haemostasis · 2024Review
- Association between intravenous fluid administration and endothelial glycocalyx shedding in humans: a systematic review.Intensive care medicine experimental · 2024Review
- Potential of acetaminophen on the sublingual microcirculation and peripheral tissue perfusion of febrile septic patients: prospective observational study.Annals of intensive care · 2024Article
- Low postoperative perfused vessel density is associated with increased soluble endothelial cell adhesion molecules during circulatory shock after cardiac surgery.Microvascular research · 2023Article
- Miniaturized microscope for non-invasive imaging of leukocyte-endothelial interaction in human microcirculation.Scientific reports · 2023Article
- Impairment of Mesenteric Perfusion as a Marker of Major Bleeding in Trauma Patients.Journal of clinical medicine · 2023Review
- End organ perfusion and pediatric microcirculation assessment.Frontiers in pediatrics · 2023Review
- Assessment of the microvascular perfusion using sidestream dark-field imaging in healthy newborn foals.Veterinary medicine and science · 2023Article
- Microcirculation-guided treatment improves tissue perfusion and hemodynamic coherence in surgical patients with septic shock.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Variability of microcirculatory measurements in healthy volunteers.Scientific reports · 2022Article
- Article
- Association of Preoperative Basal Inflammatory State, Measured by Plasma suPAR Levels, with Intraoperative Sublingual Microvascular Perfusion in Patients Undergoing Major Non-Cardiac Surgery.Journal of clinical medicine · 2022Article
- Anisodamine hydrobromide ameliorates cardiac damage after resuscitation.Experimental and therapeutic medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Various noninvasive microscopic camera technologies have been used to visualize the sublingual microcirculation in patients. We describe a comprehensive approach to bedside in vivo sublingual microcirculation video image capture and analysis techniques in the human clinical setting. We present a user perspective and guide suitable for clinical researchers and developers interested in the capture and analysis of sublingual microcirculatory flow videos. We review basic differences in the cameras, optics, light sources, operation, and digital image capture. We describe common techniques for image acquisition and discuss aspects of video data management, including data transfer, metadata, and database design and utilization to facilitate the image analysis pipeline. We outline image analysis techniques and reporting including video preprocessing and image quality evaluation. Finally, we propose a framework for future directions in the field of microcirculatory flow videomicroscopy acquisition and analysis. Although automated scoring systems have not been sufficiently robust for widespread clinical or research use to date, we discuss promising innovations that are driving new development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.