ArticleAnalytical chemistry2016
Carbon-Based Solid-State Calcium Ion-Selective Microelectrode and Scanning Electrochemical Microscopy: A Quantitative Study of pH-Dependent Release of Calcium Ions from Bioactive Glass.
Article in Analytical chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 50 citations in OpenAlex.
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- Micro-Sized pH Sensors Based on Scanning Electrochemical Probe Microscopy.Micromachines · 2022Review
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- Calibration-free Solid-State Ion-Selective Electrode Based on a Polarized PEDOT/PEDOT-S-Doped Copolymer as Back Contact.Analytical chemistry · 2022Article
- Real-time monitoring of the pH microenvironment at the interface of multispecies biofilm and dental composites.Analytica chimica acta · 2022Article
- Development of Carcinoembryonic Antigen Rapid Detection System Based on Platinum Microelectrode.Frontiers in chemistry · 2022Article
- Biodegradation behaviour of Fe-based alloys in Hanks' Balanced Salt Solutions: Part II. The evolution of local pH and dissolved oxygen concentration at metal interface.Bioactive materials · 2022Article
- Multifunctional dendritic molecular probe for selective detection of CuThe Analyst · 2021Article
- Anodic Stripping Voltammetry on a Carbon-based Ion-Selective Electrode.Electrochimica acta · 2021Article
- Scanning electrochemical microscopy and its potential for studying biofilms and antimicrobial coatings.Analytical and bioanalytical chemistry · 2020Review
- Dendritic Hydrogel Bioink for 3D Printing of Bacterial Microhabitat.ACS applied bio materials · 2019Article
- A Chemical Approach to Optimizing Bioactive Glass Dental Composites.Journal of dental research · 2019Article
- Quantifying microbial chatter: scanning electrochemical microscopy as a tool to study interactions in biofilms.Proceedings. Mathematical, physical, and engineering sciences · 2018Review
- Review
- Electrochemical imaging of cells and tissues.Chemical science · 2018Review
- Real-Time Metabolic Interactions between Two Bacterial Species Using a Carbon-Based pH Microsensor as a Scanning Electrochemical Microscopy Probe.Analytical chemistry · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Solid-state ion-selective electrodes are used as scanning electrochemical microscope (SECM) probes because of their inherent fast response time and ease of miniaturization. In this study, we report the development of a solid-state, low-poly(vinyl chloride), carbon-based calcium ion-selective microelectrode (Ca(2+)-ISME), 25 μm in diameter, capable of performing an amperometric approach curve and serving as a potentiometric sensor. The Ca(2+)-ISME has a broad linear response range of 5 μM to 200 mM with a near Nernstian slope of 28 mV/log[a(Ca(2+))]. The calculated detection limit for Ca(2+)-ISME is 1 μM. The selectivity coefficients of this Ca(2+)-ISME are log K(Ca(2+),A) = -5.88, -5.54, and -6.31 for Mg(2+), Na(+), and K(+), respectively. We used this new type of Ca(2+)-ISME as an SECM probe to quantitatively map the chemical microenvironment produced by a model substrate, bioactive glass (BAG). In acidic conditions (pH 4.5), BAG was found to increase the calcium ion concentration from 0.7 mM ([Ca(2+)] in artificial saliva) to 1.4 mM at 20 μm above the surface. In addition, a solid-state dual SECM pH probe was used to correlate the release of calcium ions with the change in local pH. Three-dimensional pH and calcium ion distribution mapping were also obtained by using these solid-state probes. The quantitative mapping of pH and Ca(2+) above the BAG elucidates the effectiveness of BAG in neutralizing and releasing calcium ions in acidic conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.