Evidence map›Paper›PMID 26861473›Full record

ArticleInternational ophthalmology2016

Plasma adropin level in patients with pseudoexfoliation.

Tevfik Oğurel, Reyhan Oğurel, Mustafa Topuz, Nurgül Örnek, Kemal Örnek

Abstract read
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In one paragraph

Article in International ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. The correlation between pseudoexfoliation syndrome and the Triglyceride-Glucose index.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tevfik OğurelDepartment of Ophthalmology, Kırıkkale University Medical Faculty, Kırıkkale University Campus, Ankara Road 6. Km, Yahsihan, 71100, Kirikkale, Turkey. ogureltevfik@hotmail.com.
Reyhan OğurelDepartment of Ophthalmology, Kırıkkale University Medical Faculty, Kırıkkale University Campus, Ankara Road 6. Km, Yahsihan, 71100, Kirikkale, Turkey.
Mustafa TopuzDepartment of Cardiology, Adana Education and Research Hospital, 01100, Adana, Turkey.
Nurgül ÖrnekDepartment of Ophthalmology, Kırıkkale University Medical Faculty, Kırıkkale University Campus, Ankara Road 6. Km, Yahsihan, 71100, Kirikkale, Turkey.
Kemal ÖrnekDepartment of Ophthalmology, Kırıkkale University Medical Faculty, Kırıkkale University Campus, Ankara Road 6. Km, Yahsihan, 71100, Kirikkale, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate plasma adropin levels in patients with pseudoexfoliation (PEX). This retrospective case-control study included 35 patients with PEX and 35 individuals without PEX who served as controls. Plasma adropin levels with triglycerides, total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and haemoglobin A1c (HGBA1C) concentrations were measured in both groups. The mean serum adropin levels were 3.24 ± 0.95 ng/mL (range, 1.90-7.88 ng/mL) in patients with PEX syndrome and 5.78 ± 2.85 ng/mL (range, 2.08-5.41 ng/mL) in PEX glaucoma patients. There was no statistically significant difference in mean adropin levels between PEX syndrome and PEX glaucoma patients. However, similar adropin levels were found in the PEX glaucoma patients and the control group (P > 0.05). The mean serum adropin levels were 3.34 ± 0.89 ng/mL (range, 1.90-5.39 ng/mL) in the PEX group and 5.78 ± 2.85 ng/mL (range, 3.08-11.06 ng/mL) in the control group. The mean serum adropin level of the PEX group was significantly lower than that of the control group (P < 0.001). There were no significant differences between the two groups in terms of serum glucose, total cholesterol, LDL, HDL, HGBA1C, triglycerides levels, or body mass index (all P > 0.05). Adropin level is lower in patients with PEX.

Indexed as

AgedBiomarkersBlood ProteinsCase-Control StudiesCholesterolExfoliation SyndromeFemaleGlaucoma, Open-AngleGlycated HemoglobinHumansIntercellular Signaling Peptides and ProteinsIntraocular PressureMaleMiddle AgedPeptidesRetrospective StudiesBiomarkersBlood ProteinsCholesterolEnho protein, humanGlycated Hemoglobinhemoglobin A1c protein, humanIntercellular Signaling Peptides and ProteinsPeptidesAdropinGlaucomaPseudoexfoliation syndrome

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.