ArticleBMC evolutionary biology2016
Intrinsic differences between males and females determine sex-specific consequences of inbreeding.
Article in BMC evolutionary biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Sex-specific inbreeding depression: A meta-analysis.Ecology letters · 2022Pooled it
- Maternal inheritance of primary sex ratios in the dark-winged fungus gnat Lycoriella ingenua.Heredity · 2026Article
- Variation in inbreeding depression within and among Caenorhabditis species.G3 (Bethesda, Md.) · 2025Article
- Limited inbreeding avoidance at the gamete level despite inbreeding depression in Atlantic salmon (Salmo salar).The Journal of animal ecology · 2025Article
- Sex-Linked Differentiation in Commercially Exploited Fishes: Rethinking Population Structure in Dynamic Marine Environments.Global change biology · 2025Article
- Integrated analyses of transcriptome, metabolome and floral B-class genes reveal sexual dimorphism in Eucommia ulmoides.BMC plant biology · 2025Article
- Parental Consanguinity and Family History in Relation to Psoriasis and the Role of Sex: A Case-Control Study.Human heredity · 2025Article
- Widespread sex ratio polymorphism inRoyal Society open science · 2023Article
- Inheritance of hormonal stress response and temperament in infant rhesus macaques (Macaca Mulatta): Nonadditive and sex-specific effects.Behavioral neuroscience · 2022Article
- Article
- Inbreeding affected differently on observations distribution of a growth trait in Iranian Baluchi sheep.Animal bioscience · 2021Article
- Recessive Z-linked lethals and the retention of haplotype diversity in a captive butterfly population.Heredity · 2020Article
- Sex-specific impact of inbreeding on pathogen load in the striped dolphin.Proceedings. Biological sciences · 2020Article
- A large close relative of C. elegans is slow-developing but not long-lived.BMC evolutionary biology · 2019Article
- The role of genetic diversity in the evolution and maintenance of environmentally-cued, male alternative reproductive tactics.BMC evolutionary biology · 2019Article
- Sex-specific effects of inbreeding on reproductive senescence.Proceedings. Biological sciences · 2018Article
- Runs of homozygosity: windows into population history and trait architecture.Nature reviews. Genetics · 2018Review
- Selection for long and short sleep duration in Drosophila melanogaster reveals the complex genetic network underlying natural variation in sleep.PLoS genetics · 2017Article
- Experimental Evolution withGenetics · 2017Review
- Accumulation of Deleterious Mutations Near Sexually Antagonistic Genes.G3 (Bethesda, Md.) · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInbreeding increases homozygosity and exposes deleterious recessive alleles, generally decreasing the fitness of inbred individuals. Interestingly, males and females are usually affected differently by inbreeding, though the more vulnerable sex depends on the species and trait measured.
resultsWe used the soil-dwelling nematode Caenorhabditis remanei to examine sex-specific inbreeding depression across nine lineages, five levels of inbreeding, and hundreds of thousands of progeny. Female nematodes consistently suffered greater fitness losses than their male counterparts, especially at high levels of inbreeding.
conclusionsThese results suggest that females experience stronger selection on genes contributing to reproductive traits. Inbreeding depression in males may be further reduced by sex chromosome hemizygosity, which affects the dominance of some mutations, as well as by the absence of sexual selection. Determining the relative contributions of sex-specific expression, genes on the sex chromosomes, and the environment they are filtered through-including opportunities for sexual selection-may explain the frequent though inconsistent records of sex differences in inbreeding depression, along with their implications for conservation and the evolution of mating systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.