SynthesisHernia : the journal of hernias and abdominal wall surgery2016
Methods of abdominal wall expansion for repair of incisional herniae: a systematic review.
Synthesis in Hernia : the journal of hernias and abdominal wall surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 4 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- Botulinum toxin A in complex incisional hernia repair: a systematic review.Hernia : the journal of hernias and abdominal wall surgery · 2024Pooled it
- Is there a role for botulinum toxin A in the emergency setting for delayed abdominal wall closure in the management of the open abdomen? A systematic review.Annals of the Royal College of Surgeons of England · 2023Pooled it
- Prehabilitation of complex ventral hernia patients with Botulinum: a systematic review of the quantifiable effects of Botulinum.Hernia : the journal of hernias and abdominal wall surgery · 2021Pooled it
- A systematic review of the use of progressive preoperative pneumoperitoneum since its inception.Hernia : the journal of hernias and abdominal wall surgery · 2021Pooled it
- Favorable one-year outcomes despite residual fascial tension after ventral hernia repair with transversus abdominis release.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- A practical algorithm for the combined use of preoperative progressive pneumoperitoneum and botulinum toxin A in large incisional hernia repair: learnings after 15 years of experience.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Staged Management of Traumatic Diaphragmatic Hernia With Open Abdomen: A Case Report on Successful Abdominal Wall Reconstruction.Clinical case reports · 2025Article
- A reproducible rat model for predicting incisional hernia recurrence: insights for clinical translation.Scientific reports · 2025Article
- Complications related to the prehabilitation with preoperative pneumoperitoneum in loss of domain hernias: our experience in 180 consecutive cases.Hernia : the journal of hernias and abdominal wall surgery · 2024Observational
- Prevention of component separation in complex abdominal wall surgery by Botox prehabilitation: a propensity-matched study.Hernia : the journal of hernias and abdominal wall surgery · 2024Article
- Volumetry after botulinum toxin A: the impact on abdominal wall compliance and endotracheal pressure.Hernia : the journal of hernias and abdominal wall surgery · 2024Article
- Comparison of two-dimensional measurement with three-dimensional volume rendering for the assessment of loss of domain in incisional hernia patients.Hernia : the journal of hernias and abdominal wall surgery · 2023Article
- Reading a preoperative CT scan to guide complex abdominal wall reconstructive surgery.Hernia : the journal of hernias and abdominal wall surgery · 2023Article
- Preoperative Progressive Pneumoperitoneum in the Treatment of Hernias With Loss of Domain. Our Experience in 50 Cases.Journal of abdominal wall surgery : JAWS · 2023Article
- An Evaluation of the Evidence Guiding Adult Midline Ventral Hernia Repair.Surgery journal (New York, N.Y.) · 2022Review
- [Management of lateral abdominal wall hernias].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2022Review
- Technique of Abdominal Wall Tissue Expansion for the Treatment of Massive Complicated Ventral Hernias.Plastic and reconstructive surgery. Global open · 2022Article
- Risk Factor-Driven Prehabilitation Prior to Abdominal Wall Reconstruction to Improve Postoperative Outcome. A Narrative Review.Journal of abdominal wall surgery : JAWS · 2022Review
- Management of complex hernias with loss of domain using daily and fractioned preoperative progressive pneumoperitoneum: a retrospective single-center cohort study.Hernia : the journal of hernias and abdominal wall surgery · 2021Article
- Adjunct botox to preoperative progressive pneumoperitoneum for incisional hernia with loss of domain: no additional effect but may improve outcomes.Hernia : the journal of hernias and abdominal wall surgery · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo systematically review the available literature regarding methods for abdominal wall expansion and compare the outcome of primary fascial closure rates.
methodsA systematic search of Pubmed and Embase databases was conducted using the search terms "Abdominal wall hernia", "ventral hernia", "midline hernia", "Botulinum toxin", "botox", "dysport", "progressive preoperative pneumoperitoneum", and "tissue expanders". Study quality was assessed using the Methodological Index for Non-Randomised Studies.
results21 of the 105 studies identified met the inclusion criteria. Progressive preoperative pneumoperitoneum (PPP) was performed in 269 patients across 15 studies with primary fascial closure being achieved in 226 (84%). 16 patients had a recurrence (7.2%) and the complication rate was 12% with 2 reported mortalities. There were 4 studies with 14 patients in total undergoing abdominal wall expansion using tissue expanders with a fascial closure rate of 92.9% (n = 13). A recurrence rate of 10.0% (n = 1) was reported with 1 complication and no mortalities. Follow up ranged from 3 to 36 months across the studies. There were 2 studies reporting the use of botulinum toxin with 29 patients in total. A primary fascial closure rate of 100% (n = 29) was demonstrated although a combination of techniques including component separation and Rives-Stoppa repair were used. There were no reported complications related to the use of Botulinum Toxin. However, the short-term follow up in many cases and the lack of routine radiological assessment for recurrence suggests that the recurrence rate has been underestimated.
conclusionsPPP, tissue expanders and Botulinum toxin are safe and feasible methods for abdominal wall expansion prior to incisional hernia repair. In combination with existing techniques for repair, these methods may help provide the crucial extra tissue mobility required to achieve primary closure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.