Evidence map›Paper›PMID 26860504›Full record

ReviewTranslational stroke research2016

Strain-Related Differences in the Immune Response: Relevance to Human Stroke.

Kyra J Becker

Abstract readReview
In one paragraph

Review in Translational stroke research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  16. Review
  17. Improving natural product research translation: From source to clinical trial.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  18. Article
  19. Article
  20. Virus envelope tissue factor promotes infection in mice.Journal of thrombosis and haemostasis : JTH · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Kyra J BeckerDepartment of Neurology, University of Washington School of Medicine, Harborview Medical Center, 325 9th Ave, Box 359775, Seattle, WA, 98104-2499, USA. kjb@uw.edu.
University of Washington · US

Funding

Sensitization to Brain Antigens Following StrokeR01NS056457 · NINDS · UNIVERSITY OF WASHINGTON · PI BECKER, KYRA J · 2006 to 2015
$3.0M
NINDS NIH HHS R01 NS056457
6 · The paper itself

Abstract

There are significant differences in the immune response and in the susceptibility to autoimmune diseases among rodent strains. It would thus be expected that the contribution of the immune response to cerebral ischemic injury would also differ among rodent strains. More importantly, there are significant differences between the immune responses of rodents and humans. All of these factors are likely to impact the successful translation of immunomodulatory therapies from experimental rodent models to patients with stroke.

Indexed as

Disease Models, AnimalAge FactorsAnimalsCytokinesHumansRodentiaSex FactorsSpecies SpecificityStrokeCytokinesEAEImmune responseImmunologyStrainStroke

Identifiers

PMID26860504
PMCPMC4929040
OpenAlexW2266505261

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.