Evidence map›Paper›PMID 26860393›Full record

ArticleScientific reports2016

Luminescence- and nanoparticle-mediated increase of light absorption by photoreceptor cells: Converting UV light to visible light.

Lei Li, Sunil K Sahi, Mingying Peng, Eric B Lee, Lun Ma, Jennifer L Wojtowicz, John H Malin, Wei Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Mitochondrial dysfunction in glaucomatous degeneration.International journal of ophthalmology · 2023
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Lei LiDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.
Sunil K SahiDepartment of Physics, and Center for Security Advances via Applied Nanotechnology, University of Texas, Arlington, TX 76019, USA.
Mingying PengThe State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou, China 510641.
Eric B LeeDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.
Lun MaDepartment of Physics, and Center for Security Advances via Applied Nanotechnology, University of Texas, Arlington, TX 76019, USA.
Jennifer L WojtowiczDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.
John H MalinDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.
Wei ChenThe State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou, China 510641.
University of Notre Dame · USSouth China University of Technology · CNApplied Nanotech (United States) · USThe University of Texas at Arlington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We developed new optic devices - singly-doped luminescence glasses and nanoparticle-coated lenses that convert UV light to visible light - for improvement of visual system functions. Tb(3+) or Eu(3+) singly-doped borate glasses or CdS-quantum dot (CdS-QD) coated lenses efficiently convert UV light to 542 nm or 613 nm wavelength narrow-band green or red light, or wide-spectrum white light, and thereby provide extra visible light to the eye. In zebrafish (wild-type larvae and adult control animals, retinal degeneration mutants, and light-induced photoreceptor cell degeneration models), the use of Tb(3+) or Eu(3+) doped luminescence glass or CdS-QD coated glass lenses provide additional visible light to the rod and cone photoreceptor cells, and thereby improve the visual system functions. The data provide proof-of-concept for the future development of optic devices for improvement of visual system functions in patients who suffer from photoreceptor cell degeneration or related retinal diseases.

Indexed as

LightOptical DevicesUltraviolet RaysAnimalsDisease Models, AnimalNanoparticlesPhotoreceptor CellsRetinal DegenerationZebrafish

Identifiers

PMID26860393
PMCPMC4748410
OpenAlexW2261486884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.