Evidence map›Paper›PMID 26859349›Full record

ArticleDevelopmental cell2016

How Toll Met Hippo.

Yingchao Nie, Y Tony Ip

Abstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Yingchao NieProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Y Tony IpProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address: tony.ip@umassmed.edu.

Funding

Genetic analysis of damage-induced intestinal stem cell division in DrosophilaR01DK083450 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI IP, Y. TONY · 2010 to 2024
$4.7M
Homeostatic signaling in the Drosophila intestineR01GM107457 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI IP, Y. TONY · 2015 to 2018
$1.3M
NIDDK NIH HHS R01 DK083450NIGMS NIH HHS R01 GM107457
6 · The paper itself

Abstract

Toll and Hippo are two seemingly disparate pathways that regulate innate immunity and tissue growth, respectively. Reporting recently in Cell, Liu et al. (2016) tie them together by demonstrating that microbial infection activates Toll, which then signals to both pathways to modulate the antimicrobial response.

Indexed as

Immunity, InnateSignal TransductionAnimalsDrosophila melanogasterMale

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.