ReviewEndocrinology2016
Developmental Programming, a Pathway to Disease.
Review in Endocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
131 citing papers in PubMed, 3 syntheses or guidelines pooled it, 217 citations in OpenAlex.
- Impacts of Consumption of Ultra-Processed Foods on the Maternal-Child Health: A Systematic Review.Frontiers in nutrition · 2022Pooled it
- Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Examining the predictive accuracy of metabolomics for small-for-gestational-age babies: a systematic review.BMJ open · 2019Pooled it
- Trial
- Portable HEPA Filter Air Cleaner Use during Pregnancy and Children's Cognitive Performance at Four Years of Age: The UGAAR Randomized Controlled Trial.Environmental health perspectives · 2022Trial
- Phylum level differences in the gut bacteria of nursing infants and growth-related decreases in iron reserves are associated with the microstructural organization of cortical white matter tracts in rhesus monkeys.Neurobiology of stress · 2026Article
- Review
- Hypertensive disorders of pregnancy contribute to developmental and metabolic multimorbidity in preterm infants.Nature communications · 2026Article
- The Motor Neuromuscular Axis: The Overlooked Element of Developmental Programming in Diabetes and Metabolic Syndrome.International journal of molecular sciences · 2026Review
- From Parallel Programming to Bidirectional Crosstalk: The Brain-Kidney Axis in Cardiovascular-Kidney-Metabolic Syndrome.Antioxidants (Basel, Switzerland) · 2026Review
- Maternal low-sodium diet impairs hippocampal neurogenesis and cognition in adult mouse offspring.American journal of physiology. Regulatory, integrative and comparative physiology · 2026Article
- Prenatal and postnatal droughts interact in shaping cognitive development.Communications medicine · 2026Article
- Resveratrol and Redox Regulation in Cardiovascular Disease Across the Life Course: Mechanistic and Translational Perspectives.Antioxidants (Basel, Switzerland) · 2026Review
- Melatonin as a Redox Modulator in Developmental Programming: Implications for Cardiovascular-Kidney-Metabolic Risk.International journal of molecular sciences · 2026Review
- Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice.Nature communications · 2026Article
- Protective versus risky: the complex relationship between prenatal fluoride exposure and birth outcomes in a Chinese large-scale population study.Environmental health : a global access science source · 2026Article
- The fetal exposome: cellular and epigenetic programming of neonatal immune function.Frontiers in immunology · 2026Review
- How Early-Life Programming During Embryogenesis Imprints Cellular Memory.International journal of molecular sciences · 2025Review
- RAMEN: Dissecting individual, additive and interactive gene-environment contributions to DNA methylome variability in cord blood.Genome biology · 2025Article
- Comprehensive Review of the Impact of Maternal Stress on Fetal Development.Pediatric discovery · 2025Review
71 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Accumulating evidence suggests that insults occurring during the perinatal period alter the developmental trajectory of the fetus/offspring leading to long-term detrimental outcomes that often culminate in adult pathologies. These perinatal insults include maternal/fetal disease states, nutritional deficits/excess, stress, lifestyle choices, exposure to environmental chemicals, and medical interventions. In addition to reviewing the various insults that contribute to developmental programming and the benefits of animal models in addressing underlying mechanisms, this review focuses on the commonalities in disease outcomes stemming from various insults, the convergence of mechanistic pathways via which various insults can lead to common outcomes, and identifies the knowledge gaps in the field and future directions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.