ArticleInfluenza and other respiratory viruses2016
Clinical outcomes in outpatient respiratory syncytial virus infection in immunocompromised children.
Article in Influenza and other respiratory viruses, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Burden and Risk Factors for Severe Respiratory Syncytial Virus Infection among Pediatric Hematopoietic Cell Transplant Recipients.Journal of the Pediatric Infectious Diseases Society · 2026Article
- Clinical research on secure multi-party computation technology for auxiliary respiratory pathogen diagnosis and treatment design in preschool-aged children.Frontiers in pediatrics · 2026Article
- Review
- Identification of Lower Respiratory Tract Pathogens in Cancer Patients: Insights into Fatal Outcomes.Microorganisms · 2024Article
- Review
- Estimating the Incidence of First RSV Hospitalization in Children Born in Ontario, Canada.Journal of the Pediatric Infectious Diseases Society · 2023Article
- Implications of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Pandemic on the Epidemiology of Pediatric Respiratory Syncytial Virus Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- A Multicenter Consortium to Define the Epidemiology and Outcomes of Pediatric Solid Organ Transplant Recipients With Inpatient Respiratory Virus Infection.Journal of the Pediatric Infectious Diseases Society · 2019Observational
- Characteristics and Outcomes of Coronavirus Infection in Children: The Role of Viral Factors and an Immunocompromised State.Journal of the Pediatric Infectious Diseases Society · 2019Article
- Role of Type I Interferon (IFN) in the Respiratory Syncytial Virus (RSV) Immune Response and Disease Severity.Frontiers in immunology · 2019Review
- Burden of severe RSV disease among immunocompromised children and adults: a 10 year retrospective study.BMC infectious diseases · 2018Observational
- Case report of severe myocarditis in an immunocompromised child with Respiratory Syncytial Virus infection.BMC pediatrics · 2018Article
- Respiratory Viral Infections in Patients With Cancer or Undergoing Hematopoietic Cell Transplant.Frontiers in microbiology · 2018Review
- Respiratory Viral Infections in Solid Organ and Hematopoietic Stem Cell Transplantation.Clinics in chest medicine · 2017Review
- Defining the Incidence and Associated Morbidity and Mortality of Severe Respiratory Syncytial Virus Infection Among Children with Chronic Diseases.Infectious diseases and therapy · 2017Review
- Clinical outcomes in outpatient respiratory syncytial virus infection in immunocompromised children.Influenza and other respiratory viruses · 2016Article
- Improvement in Palivizumab Administration in Severely Immunocompromised Children: A Single-institution Quality Improvement Initiative.Pediatric quality & safetyArticle
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundImmunocompromised patients are at high risk for morbidity and mortality due to respiratory syncytial virus (RSV) infection. Increasingly, pediatric patients with malignancy or undergoing transplantation are managed primarily as outpatients. Data regarding the clinical presentation and outcomes of RSV in the outpatient pediatric immunocompromised population are limited.
methodsWe performed a retrospective cohort study of children with hematologic malignancy or hematopoietic or solid organ transplant with laboratory-confirmed RSV infection diagnosed as outpatients at an academic medical center between 2008 and 2013.
resultsOf 54 patients with RSV detected while outpatients, 15 (28%) were hospitalized, 7 (13%) received ribavirin, and one (2%) received intravenous immunoglobulin. One (2%) patient was critically ill, but there were no deaths due to RSV infection. Fever (P < 0·01) was associated with increased risk of hospitalization.
conclusionsMost immunocompromised children with RSV detected while outpatients did not require hospitalization or receive antiviral treatment. Potential studies of RSV therapies should consider inclusion of patients in an ambulatory setting.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.