Evidence map›Paper›PMID 26859079›Full record

ArticleLeukemia2016

The possible perils of targeted therapy.

U Duffner, A Abdel-Mageed, J Younge, C Tornga, K Scott, J Staddon, K Elliott, J Stumph, P Kidd

Abstract readCase ReportsLetter
PubMed Publisher
In one paragraph

Article in Leukemia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

U DuffnerDivision of Pediatric Blood & Bone marrow Transplantation at Helen DeVos Children's Hospital, Grand Rapids, MI, USA.
A Abdel-MageedDivision of Pediatric Blood & Bone marrow Transplantation at Helen DeVos Children's Hospital, Grand Rapids, MI, USA.
J YoungeDivision of Pediatric Blood & Bone marrow Transplantation at Helen DeVos Children's Hospital, Grand Rapids, MI, USA.
C TorngaDivision of Pediatric Blood & Bone marrow Transplantation at Helen DeVos Children's Hospital, Grand Rapids, MI, USA.
K ScottDivision of Pediatric Hematology/Oncology at Bronson Medical Center, Kalamazoo, MI, USA.
J StaddonDivision of Pediatric Hematology/Oncology at Bronson Medical Center, Kalamazoo, MI, USA.
K ElliottDivision of Pediatric Hematology/Oncology at Bronson Medical Center, Kalamazoo, MI, USA.
J StumphSpectrum Health and Michigan State University, Department of Pediatrics & Human Development, Grand Rapids, MI, USA.
P KiddSpectrum Health and Michigan State University, Department of Pediatrics & Human Development, Grand Rapids, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibodies, BispecificAntineoplastic Agents, ImmunologicalFemaleHistone-Lysine N-MethyltransferaseHumansLeukemia, Monocytic, AcuteMolecular Targeted TherapyMyeloid-Lymphoid Leukemia ProteinNeoplasms, Second PrimaryPrecursor B-Cell Lymphoblastic Leukemia-LymphomaYoung AdultAntibodies, BispecificAntineoplastic Agents, ImmunologicalblinatumomabHistone-Lysine N-MethyltransferaseKMT2A protein, humanMyeloid-Lymphoid Leukemia Protein

Identifiers

PMID26859079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.