ArticleCurrent opinion in behavioral sciences2016
Developmental immune activation programs adult behavior: insight from research on birds.
Article in Current opinion in behavioral sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- A review of environmental enrichment for laying hens during rearing in relation to their behavioral and physiological development.Poultry science · 2019Review
- Pre- and postnatal effects of experimentally manipulated maternal corticosterone on growth, stress reactivity and survival of nestling house wrens.Functional ecology · 2018Article
- Early-life immune activation increases song complexity and alters phenotypic associations between sexual ornaments.Functional ecology · 2017Article
- Flight performance in the altricial zebra finch: Developmental effects and reproductive consequences.Ecology and evolution · 2017Article
- Neuroendocrine-immune circuits, phenotypes, and interactions.Hormones and behavior · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Immune activation early in life can program adult behavioral expression. Previous research on birds has documented effects of parasite exposure and immune challenges early in life on dispersal, song, personality, learning and feather pecking. However, the mechanisms responsible for mediating these programming effects are unknown. Candidate brain regions that may be most sensitive include the hippocampus and HVC. Without an understanding of mechanism, it is difficult to assess if programmed behaviors represent pathological side effects or behavioral modifications with benefits to either hosts or parasites. Future research on birds promises to provide novel insight into the adaptive value of programming effects of early life immune activation and the capacity for selection to buffer hosts against negative effects.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.