Evidence map›Paper›PMID 26858941›Full record

ReviewFrontiers in cellular and infection microbiology2016

Riboregulators: Fine-Tuning Virulence in Shigella.

Megan E Fris, Erin R Murphy

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. The RNA Revolution in the Central Molecular Biology Dogma Evolution.International journal of molecular sciences · 2024
    Review
  2. START: A Versatile Platform for Bacterial Ligand Sensing with Programmable Performances.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  3. A Novel sRNA inFrontiers in cellular and infection microbiology · 2020
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Megan E FrisDepartment of Biological Science, Ohio University Athens, OH, USA.
Erin R MurphyDepartment of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University Athens, OH, USA.

Funding

Form and Function of Tandem Duplicate Small RNA Molecules in Shigella dysenteriaeR15AI103887 · NIAID · OHIO UNIVERSITY ATHENS · PI MURPHY, ERIN R · 2013 to 2013
$446k
Analysis of a Shigella dysenteriae Fe regulated promoterF32GM069312 · NIGMS · UNIVERSITY OF TEXAS AUSTIN · PI MURPHY, ERIN R · 2003 to 2005
$139k
NIAID NIH HHS R15 AI103887NIAID NIH HHS R15AI103887-01A1NIGMS NIH HHS F32 GM069312
6 · The paper itself

Abstract

Within the past several years, RNA-mediated regulation (ribo-regulation) has become increasingly recognized for its importance in controlling critical bacterial processes. Regulatory RNA molecules, or riboregulators, are perpetually responsive to changes within the micro-environment of a bacterium. Notably, several characterized riboregulators control virulence in pathogenic bacteria, as is the case for each riboregulator characterized to date in Shigella. The timing of virulence gene expression and the ability of the pathogen to adapt to rapidly changing environmental conditions is critical to the establishment and progression of infection by Shigella species; ribo-regulators mediate each of these important processes. This mini review will present the current state of knowledge regarding RNA-mediated regulation in Shigella by detailing the characterization and function of each identified riboregulator in these pathogens.

Indexed as

Dysentery, BacillaryGastrointestinal TractGene Expression Regulation, BacterialHumansRNA, BacterialRNA, Small UntranslatedShigellaVirulence FactorsRNA, BacterialRNA, Small UntranslatedVirulence FactorsenvironmentpathogenesisriboregulatorShigellasmall RNAsRNA

Identifiers

PMID26858941
PMCPMC4728522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.