Evidence map›Paper›PMID 26858833›Full record

ArticleAnnals of medicine and surgery (2012)2016

Are we following an algorithm for managing chronic anal fissure? A completed audit cycle.

Nicholas Farkas, Kohmal Solanki, Adam E Frampton, John Black, Ashish Gupta, Nicholas J West

Open access · diamondAbstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 13 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nicholas FarkasDepartment of General & Colorectal Surgery, Epsom & St. Helier University Hospitals NHS Trust, St. Helier Hospital, Wrythe Lane, Carshalton, Surrey, SM5 1AA, UK.
Kohmal SolankiDepartment of General & Colorectal Surgery, Epsom & St. Helier University Hospitals NHS Trust, St. Helier Hospital, Wrythe Lane, Carshalton, Surrey, SM5 1AA, UK.
Adam E FramptonDepartment of General & Colorectal Surgery, Epsom & St. Helier University Hospitals NHS Trust, St. Helier Hospital, Wrythe Lane, Carshalton, Surrey, SM5 1AA, UK.
John BlackDepartment of General & Colorectal Surgery, Epsom & St. Helier University Hospitals NHS Trust, St. Helier Hospital, Wrythe Lane, Carshalton, Surrey, SM5 1AA, UK.
Ashish GuptaDepartment of General & Colorectal Surgery, Epsom & St. Helier University Hospitals NHS Trust, St. Helier Hospital, Wrythe Lane, Carshalton, Surrey, SM5 1AA, UK.
Nicholas J WestDepartment of General & Colorectal Surgery, Epsom & St. Helier University Hospitals NHS Trust, St. Helier Hospital, Wrythe Lane, Carshalton, Surrey, SM5 1AA, UK.
Epsom and St Helier University Hospitals NHS Trust · GBSt Helier Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnal fissure is one of the commonest proctological diseases with considerable national variation in sequential treatment. We aimed to audit our compliance of chronic anal fissure (CAF) management with national guidance provided by the Association of Coloproctology of Great Britain and Ireland (ACPGBI).

methodsWe retrospectively audited patients presenting to outpatient clinics with CAF over a 6-month period. Using electronic patient records, notes and clinic letters, we compared their management with ACPGBI algorithm. A prospective re-audit was then performed.

resultsForty-one patients were included in the analysis (59% male). Sixty-eight percent (n = 28/41) of patients were appropriately started on conservative dietary therapy, of whom only 7.1% (n = 2/28) had treatment success. Eighty-nine percent (n = 25/28) were then appropriately treated with either topical diltiazem 2% or GTN 0.4%. Overall, 43.9% (n = 18/41) of all patients' entire management strategy adhered to the ACPGBI guidelines. In total, 48.8% (n = 20/41) patients had surgical treatment (excluding Botox), of which only 15% (n = 3/20) had undergone ACPGBI-compliant management. After local dissemination of results and education, the re-audit of 20 patients showed significant improvement in adherence to the guidelines (43.9% vs. 95%; P = 0.0001).

conclusionsTopical creams were the most successful treatments (50%; n = 9/18) in ACPGBI-compliant strategies. Importantly, these data suggests that compliance with the ACPGBI algorithm leads to healing without surgery in 83.3% (n = 15/18) of patients, compared to 26.1% (n = 6/23) with non-compliant methods (P = 0.0004). This highlights the benefit of early conservative and medical management of CAF, before attempting surgery.

Indexed as

AuditBotoxChronic anal fissure (CAF)DiltiazemGTNManagementSurgery

Identifiers

PMID26858833
PMCPMC4706569
OpenAlexW2211136832

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.