ArticleJournal of nanotechnology in engineering and medicine2015
Hybrid Tissue Engineering Scaffolds by Combination of Three-Dimensional Printing and Cell Photoencapsulation.
Article in Journal of nanotechnology in engineering and medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 88 citations in OpenAlex.
- Mevalonate pathway activation in Ewing sarcoma reveals a 3D-specific synergy between statins and BCL-xL inhibition.Molecular therapy. Oncology · 2026Article
- Applications and Recent Advances in 3D Bioprinting Sustainable Scaffolding Techniques.Molecules (Basel, Switzerland) · 2025Review
- Micropatterning of Confined Surfaces with Polymer Brushes by Two-Photon-Initiated Reversible Addition-Fragmentation Chain-Transfer Polymerization.Small science · 2025Article
- Recapitulating the bone extracellular matrix through 3D bioprinting using various crosslinking chemistries.Frontiers in bioengineering and biotechnology · 2025Review
- Digital Light Processing ofMaterials (Basel, Switzerland) · 2024Article
- Small molecular weight alginate gel porogen for the 3D bioprinting of microvasculature.Frontiers in bioengineering and biotechnology · 2024Article
- A review of bioengineering techniques applied to breast tissue: Mechanical properties, tissue engineering and finite element analysis.Frontiers in bioengineering and biotechnology · 2023Review
- Additive Manufacturing of Viscoelastic Polyacrylamide Substrates for Mechanosensing Studies.ACS omega · 2022Article
- Gelatin methacryloyl as environment for chondrocytes and cell delivery to superficial cartilage defects.Journal of tissue engineering and regenerative medicine · 2022Article
- Design and Synthesis of Hybrid Thermo-Responsive Hydrogels Based on Poly(2-oxazoline) and Gelatin Derivatives.Gels (Basel, Switzerland) · 2022Article
- Article
- Water-Soluble Photoinitiators in Biomedical Applications.Polymers · 2020Review
- Article
- Hybrid Bioprinting of Chondrogenically Induced Human Mesenchymal Stem Cell Spheroids.Frontiers in bioengineering and biotechnology · 2020Article
- Impact of Hydrogel Stiffness on Differentiation of Human Adipose-Derived Stem Cell Microspheroids.Tissue engineering. Part A · 2019Article
- Bone Morphogenetic Protein 2-Conjugated Silica Particles Enhanced Early Osteogenic Differentiation of Adipose Stem Cells on the Polycaprolactone Scaffold.Tissue engineering and regenerative medicine · 2019Article
- Three-dimensional modelling and three-dimensional printing in pediatric and congenital cardiac surgery.Translational pediatrics · 2018Review
- Microfabrication-Based Three-Dimensional (3-D) Extracellular Matrix Microenvironments for Cancer and Other Diseases.International journal of molecular sciences · 2018Review
- Mechanical viability of a thermoplastic elastomer hydrogel as a soft tissue replacement material.Journal of the mechanical behavior of biomedical materials · 2018Article
- Fabrication of biomimetic placental barrier structures within a microfluidic device utilizing two-photon polymerization.International journal of bioprinting · 2018Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
Three-dimensional (3D) printing offers versatile possibilities for adapting the structural parameters of tissue engineering scaffolds. However, it is also essential to develop procedures allowing efficient cell seeding independent of scaffold geometry and pore size. The aim of this study was to establish a method for seeding the scaffolds using photopolymerizable cell-laden hydrogels. The latter facilitates convenient preparation, and handling of cell suspension, while distributing the hydrogel precursor throughout the pores, before it is cross-linked with light. In addition, encapsulation of living cells within hydrogels can produce constructs with high initial cell loading and intimate cell-matrix contact, similar to that of the natural extra-cellular matrix (ECM). Three dimensional scaffolds were produced from poly(lactic) acid (PLA) by means of fused deposition modeling. A solution of methacrylamide-modified gelatin (Gel-MOD) in cell culture medium containing photoinitiator Li-TPO-L was used as a hydrogel precursor. Being an enzymatically degradable derivative of natural collagen, gelatin-based matrices are biomimetic and potentially support the process of cell-induced remodeling. Preosteoblast cells MC3T3-E1 at a density of 10 × 10
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.