Evidence map›Paper›PMID 26858752›Full record

ArticleGastroenterology research and practice2016

Characteristics of Pediatric Crohn's Disease in Saudi Children: A Multicenter National Study.

Omar I Saadah, Mohammad El Mouzan, Mohammad Al Mofarreh, Ali Al Mehaidib, Mohammad Al Edreesi, Mohammed Hasosah, Abdulrahman Al-Hussaini, Khalid AlSaleem

Abstract read
In one paragraph

Article in Gastroenterology research and practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Inflammatory Bowel Disease in Jordanian Children: A Tertiary Center Experience.Pediatric gastroenterology, hepatology & nutrition · 2025
    Article
  3. Bacterial dysbiosis in newly diagnosed treatment naïve pediatric ulcerative colitis in Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Pediatric Crohn's Disease in Bahrain.Oman medical journal · 2018
    Article
  8. Article
  9. Clinical presentation of inflammatory bowel disease in Saudi children (Single centre experience).International journal of pediatrics & adolescent medicine · 2016
    Article
  10. Incidence and clinical characteristics of pediatric inflammatory bowel disease in Oman.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
  11. Magnetic resonance enterography and bowel ultrasonography in Saudi Arabian patients with Crohn's disease: A correlation study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
  12. Diagnostic delay of pediatric inflammatory bowel disease in Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Omar I SaadahDepartment of Pediatrics, Faculty of Medicine & Inflammatory Bowel Disease Research Group, King Abdulaziz University, P.O. Box 80205, Jeddah 21589, Saudi Arabia.
Mohammad El MouzanDepartment of Pediatrics, Pediatric IBD Research Group, Prince Abdullah Bin Khalid Celiac Disease Research Chair, King Saud University, P.O. Box 2925, Riyadh 11461, Saudi Arabia.
Mohammad Al MofarrehDepartment of Gastroenterology, Al-Mofarreh Polyclinic, P.O. Box 9789, Riyadh 11423, Saudi Arabia.
Ali Al MehaidibDepartment of Pediatrics, Division of Gastroenterology, King Faisal Specialist Hospital and Research Center, P.O. Box 3354, Riyadh 11211, Saudi Arabia.
Mohammad Al EdreesiDepartment of Pediatrics, Division of Gastroenterology, Dhahran Health Center, Saudi Aramco Medical Services Organization, P.O. Box 5000, Dhahran 31311, Saudi Arabia.
Mohammed HasosahDepartment of Pediatrics, Division of Gastroenterology, King Abdulaziz Medical City, National Guard Health Affairs, P.O. Box 8202, Jeddah 21482, Saudi Arabia.
Abdulrahman Al-HussainiDivision of Gastroenterology, King Fahad Medical City, Children's Hospital, King Saud bin Abdulaziz University for Health Sciences, P.O. Box 59046, Riyadh 11525, Saudi Arabia.
Khalid AlSaleemDepartment of Pediatrics, Division of Gastroenterology, King Faisal Specialist Hospital and Research Center, P.O. Box 3354, Riyadh 11211, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims. Crohn's disease (CD) is an evolving disease in KSA. Little is known about its characteristics in the Saudi population. The aims of this study were to describe the characteristics of Saudi children with CD and to determine whether the characteristics of CD in KSA are different from those seen in Western countries. Methods. In this study, children younger than eighteen years of age diagnosed with CD between January 2003 and December 2012 were included. Results. Of 330 patients identified, 186 (56.4%) were males. The median age at diagnosis was 15.8 years. A positive family history for IBD in first-degree relatives occurred in 13.6% of patients. The most common symptoms were abdominal pain (84.2%), weight loss (75.2%), and diarrhea (71.8%). The main disease location was ileocolonic (42.1%) and the main disease behavior was nonstricturing and nonpenetrating (63.6%). Perianal involvement was seen in 60 (18.2%) patients. Laboratory findings revealed anemia in 57.9% of patients, low albumin in 34.5%, and high CRP in 39.4%. Conclusions. Saudi children with CD have lower frequency of first-degree relatives with IBD, lower prevalence of early onset disease, longer diagnostic delay, higher prevalence of growth failure, and greater frequency of stricturing and penetrating disease behavior compared to Western patients.

Identifiers

PMID26858752
PMCPMC4709618

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.