ArticleProceedings of the National Academy of Sciences of the United States of America2016
Ultrasensitive microchip based on smart microgel for real-time online detection of trace threat analytes.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Hollow microgels and their hybrids: classification, synthesis, characterization, properties and applications.Reviews in chemical engineering · 2024Article
- Encoding microcarriers for biomedicine.Smart medicine · 2023Review
- Interplay of the Influence of Crosslinker Content and Model Drugs on the Phase Transition of Thermoresponsive PNiPAM-BIS Microgels.Gels (Basel, Switzerland) · 2022Article
- Natural and Engineered Nanomaterials for the Identification of Heavy Metal Ions-A Review.Nanomaterials (Basel, Switzerland) · 2022Review
- Assessing the perfluoroalkyl acid-induced swelling of Förster resonance energy transfer-capable poly(Soft matter · 2021Article
- Thermosensitive Microgels-Decorated Magnetic Graphene Oxides for Specific Recognition and Adsorption of Pb(II) from Aqueous Solution.ACS omega · 2019Article
- Review
- In-flow real-time detection of spectrally encoded microgels for miRNA absolute quantification.Biomicrofluidics · 2016Article
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Authors and funding
8 authors.
Funding
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Abstract
Real-time online detection of trace threat analytes is critical for global sustainability, whereas the key challenge is how to efficiently convert and amplify analyte signals into simple readouts. Here we report an ultrasensitive microfluidic platform incorporated with smart microgel for real-time online detection of trace threat analytes. The microgel can swell responding to specific stimulus in flowing solution, resulting in efficient conversion of the stimulus signal into significantly amplified signal of flow-rate change; thus highly sensitive, fast, and selective detection can be achieved. We demonstrate this by incorporating ion-recognizable microgel for detecting trace Pb(2+), and connecting our platform with pipelines of tap water and wastewater for real-time online Pb(2+) detection to achieve timely pollution warning and terminating. This work provides a generalizable platform for incorporating myriad stimuli-responsive microgels to achieve ever-better performance for real-time online detection of various trace threat molecules, and may expand the scope of applications of detection techniques.
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