Evidence map›Paper›PMID 26857820›Full record

ArticleThe journal of headache and pain2015

European Headache Federation consensus on technical investigation for primary headache disorders.

D D Mitsikostas, M Ashina, A Craven, H C Diener, P J Goadsby, M D Ferrari, C Lampl, K Paemeleire, J Pascual, A Siva and 4 more

Open access · goldAbstract readConsensus Statement
In one paragraph

Article in The journal of headache and pain, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 3 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 122 citations in OpenAlex.

  1. What does a migraine aura look like?-A systematic review.The journal of headache and pain · 2025
    Pooled it
  2. Pooled it
  3. Headache and pregnancy: a systematic review.The journal of headache and pain · 2017
    Pooled it
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Clinical features of migraine with aura: a REFORM study.The journal of headache and pain · 2024
    Article
  11. Migraine Comorbidities.Life (Basel, Switzerland) · 2024
    Review
  12. Review
  13. Review
  14. Review
  15. The 5-HTNature reviews. Neurology · 2023
    Review
  16. Article
  17. Review
  18. Neurological soft signs are increased in migraine without aura: relationship with the affective status.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  19. Long COVID headache.The journal of headache and pain · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 11 institutions in 10 countries.

D D MitsikostasNeurology Department, Athens Naval Hospital, Athens, Greece. dimosmitsikostas@me.com.
M AshinaDanish Headache Center, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. ashina@dadlnet.dk.
A CravenEuropean Headache Alliance, President, Dublin, Ireland. audreycraven@migraine.ie.
H C DienerDepartment of Neurology, University Hospital Essen, University Duisburg-Essen, Essen, Germany. hans.diener@uk-essen.de.
P J GoadsbyBasic and Clinical Neurosciences, Institute of Psychiatry, Psychology and Neuroscience, and King's Clinical Research Facility, Kings College London, Wellcome Foundation Building, King's College Hospital, London, SE5 9PJ, UK. peter.goadsby@kcl.ac.uk.
M D FerrariCenter for Proteomics and Metabolomics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands. M.D.Ferrari@lumc.nl.
C LamplMedical Headache Center, Hospital Sisters of Mercy, Seilerstaette Linz, Linz, 4020, Austria. christian.lampl@bhs.at.
K PaemeleireDepartment of Neurology, Ghent University Hospital, Ghent, Belgium. Koen.Paemeleire@uzgent.be.
J PascualUniversity Hospital Marqués de Valdecilla and IDIVAL, 39011, Santander, Spain. juliopascual@telefonica.net.
A SivaDepartment of Neurology, Cerrahpasa School of Medicine, Istanbul University, Millet Cad, 34390, Capa/Istanbul, Turkey. akselsiva@gmail.com.
J OlesenDanish Headache Centre and Department of Neurology, Rigshospitalet, Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. jes.olesen@regionh.dk.
V OsipovaDepartment of Neurology, First Moscow State Medical University, Moscow, Russia. osipova_v@mail.ru.
P MartellettiDepartment of Clinical and Molecular Medicine, Sapienza University, Rome, Italy. paolo.martelletti@uniroma1.it.
EHF committee
Athens Naval & Veterans Hospital · GRGhent University Hospital · BEInstituto de Investigación Marqués de Valdecilla · ESIstanbul University · TRKing's College London · GBLeiden University Medical Center · NLRigshospitalet · DKSapienza University of Rome · ITSechenov University · RUUniversity of Copenhagen · DKUniversity of Duisburg-Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis of primary headache disorders is clinical and based on the diagnostic criteria of the International Headache Society (ICHD-3-beta). However several brain conditions may mimic primary headache disorders and laboratory investigation may be needed. This necessity occurs when the treating physician doubts for the primary origin of headache. Features that represent a warning for a possible underlying disorder causing the headache are new onset headache, change in previously stable headache pattern, headache that abruptly reaches the peak level, headache that changes with posture, headache awakening the patient, or precipitated by physical activity or Valsalva manoeuvre, first onset of headache ≥50 years of age, neurological symptoms or signs, trauma, fever, seizures, history of malignancy, history of HIV or active infections, and prior history of stroke or intracranial bleeding. All national headache societies and the European Headache Alliance invited to review and comment the consensus before the final draft. The consensus recommends brain MRI for the case of migraine with aura that persists on one side or in brainstem aura. Persistent aura without infarction and migrainous infarction require brain MRI, MRA and MRV. Brain MRI with detailed study of the pituitary area and cavernous sinus, is recommended for all TACs. For primary cough headache, exercise headache, headache associated with sexual activity, thunderclap headache and hypnic headache apart from brain MRI additional tests may be required. Because there is little and no good evidence the committee constructed a consensus based on the opinion of experts, and should be treated as imperfect.

Indexed as

Magnetic Resonance ImagingHeadache Disorders, PrimaryHumansNeuroimagingPhysical ExaminationBrain MRIConsensusDiagnostic testsMigrainePrimary headache disordersTACsTension-type headache

Identifiers

PMID26857820
PMCPMC4747925
OpenAlexW2276551150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.