ArticleDrug testing and analysis
Dietary supplements quality analysis tools from the United States Pharmacopeia.
Article in Drug testing and analysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Compendial Perspectives on Botanical Identity Testing.Journal of natural products · 2026Review
- Assessment of Physicochemical Parameters and Contaminants in Herbal Dietary Supplements Used in the Treatment of Inflammatory Bowel Disease.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Dietary Supplements with Proline-A Comprehensive Assessment of Their Quality.Life (Basel, Switzerland) · 2023Article
- Hand-Portable Miniaturized Liquid Chromatography for the Determination of Chlorogenic Acids in Dietary Supplements.Antioxidants (Basel, Switzerland) · 2022Article
- Enhancing Testing Laboratory Engagement in Plant DNA Barcoding through a Routine Workflow-A Case Study on Chinese Materia Medica (CMM).Plants (Basel, Switzerland) · 2022Article
- Dietary supplements: When too much of a good thing becomes harmful.Clinical case reports · 2021Article
- Capillary Liquid Chromatography for the Determination of Terpenes in Botanical Dietary Supplements.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Validation of a Triplex Quantitative Polymerase Chain Reaction Assay for Detection and Quantification of Traditional Protein Sources,Frontiers in plant science · 2021Article
- The Importance of Reference Materials and Method Validation for Advancing Research on the Health Effects of Dietary Supplements and Other Natural Products.Frontiers in nutrition · 2021Review
- Current regulatory guidelines and resources to support research of dietary supplements in the United States.Critical reviews in food science and nutrition · 2020Review
- Selection and characterization of botanical natural products for research studies: a NaPDI center recommended approach.Natural product reports · 2019Review
- Poor chemical and microbiological quality of the commercial milk thistle-based dietary supplements may account for their reported unsatisfactory and non-reproducible clinical outcomes.Scientific reports · 2019Article
- Determination of Peptide Profile Consistency and Safety of Collagen Hydrolysates as Quality Attributes.Journal of food science · 2019Article
- Integrated analytical assets aid botanical authenticity and adulteration management.Fitoterapia · 2018Review
- Variability in Potency Among Commercial Preparations of Berberine.Journal of dietary supplements · 2018Article
- Retrospective Study of Reported Adverse Events Due to Complementary Health Products in Singapore From 2010 to 2016.Frontiers in medicine · 2018Article
- Dietary supplements quality analysis tools from the United States Pharmacopeia.Drug testing and analysisArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The United States Food and Drug Administration (FDA) issued the dietary supplement (DS) current good manufacturing practice (GMP) regulations in compliance with the mandate from the Dietary Supplements Health and Education Act (DSHEA), with the intention of protecting public health by ensuring the quality of DS. The GMP regulations require manufacturers to establish their own quality specifications for identity, purity, strength, composition, and absence of contaminants. Numerous FDA-conducted GMP inspections found that the private specifications set by these manufacturers are often insufficient to ensure adequate quality of dietary ingredients and DS. Wider use of the public standards developed by the United States Pharmacopeial Convention (USP), in conjunction with GMP compliance, can help ensure quality and consistency of DS as they do for medicines. Public health protection could be enhanced by strengthening the GMP provisions to require conformance with relevant United States Pharmacopeia-National Formulary (USP-NF) standards, or in the absence of USP standards, other public compendial standards. Another serious concern is the presence of synthetic drugs and drug analogues in products marketed as DS. Use of the new USP General Chapter Adulteration of Dietary Supplements with Drugs and Drug Analogs <2251> may reduce the exposure of consumers to dangerous drugs disguised as DS. Copyright © 2016 John Wiley & Sons, Ltd.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.