ArticlePediatric nephrology (Berlin, Germany)2016
Perceived appetite and clinical outcomes in children with chronic kidney disease.
Article in Pediatric nephrology (Berlin, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00327860 (Chronic Kidney Disease in Children Prospective Cohort Study), which is not on this map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)
Who cites it
17 citing papers in PubMed.
- Ten tips on how to optimize nutrition in children with chronic kidney disease or on dialysis.Clinical kidney journal · 2026Review
- Association of Dietary Micronutrient Intake and the Metabolome in Children with CKD.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Investigation of normalized protein catabolic rate as a marker of nutritional status in infants and children receiving chronic hemodialysis: a longitudinal cohort study.Pediatric nephrology (Berlin, Germany) · 2025Article
- Malnutrition management in children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2025Review
- Nutritional management of the child with chronic kidney disease and on dialysis.Pediatric nephrology (Berlin, Germany) · 2025Review
- Assessment of Undernutrition in Pediatric Chronic Kidney Disease - Gaps and Opportunities.Frontiers in pediatrics · 2022Article
- Monitoring dialysis adequacy: history and current practice.Pediatric nephrology (Berlin, Germany) · 2021Article
- Longitudinal outcomes of body mass index in overweight and obese children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2021Article
- Assessment of nutritional status in children with kidney diseases-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce.Pediatric nephrology (Berlin, Germany) · 2021Review
- Body composition and arterial stiffness in pediatric patients with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2019Article
- Chronic Kidney Disease: Treatment of Comorbidities I: (Nutrition, Growth, Neurocognitive Function, and Mineral Bone Disease).Current treatment options in pediatrics · 2019Article
- Associations Between Weight Loss, Kidney Function Decline, and Risk of ESRD in the Chronic Kidney Disease in Children (CKiD) Cohort Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2018Observational
- Muscle wasting in chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2018Review
- Optimizing Enteral Nutrition for Growth in Pediatric Chronic Kidney Disease (CKD).Frontiers in pediatrics · 2018Review
- Waist Circumference and Body Mass Index in Children with Chronic Kidney Disease and Metabolic, Cardiovascular, and Renal Outcomes.The Journal of pediatrics · 2017Observational
- Relationships of Measured Iohexol GFR and Estimated GFR With CKD-Related Biomarkers in Children and Adolescents.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2017Article
- Lack of hepcidin ameliorates anemia and improves growth in an adenine-induced mouse model of chronic kidney disease.American journal of physiology. Renal physiology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundChildren with chronic kidney disease (CKD) may have impaired caloric intake through a variety of mechanisms, with decreased appetite as a putative contributor. In adult CKD, decreased appetite has been associated with poor clinical outcomes. There is limited information about this relationship in pediatric CKD.
methodsA total of 879 participants of the Chronic Kidney Disease in Children (CKiD) study were studied. Self-reported appetite was assessed annually and categorized as very good, good, fair, or poor/very poor. The relationship between appetite and iohexol or estimated glomerular filtration rate (ieGFR), annual changes in anthropometrics z-scores, hospitalizations, emergency room visits, and quality of life were assessed.
resultsAn ieGFR < 30 ml/min per 1.73 m(2) was associated with a 4.46 greater odds (95 % confidence interval: 2.80, 7.09) of having a worse appetite than those with ieGFR >90. Appetite did not predict changes in height, weight, or BMI z-scores. Patients not reporting a very good appetite had more hospitalizations over the next year than those with a very good appetite. Worse appetite was significantly associated with lower parental and patient reported quality of life.
conclusionsSelf-reported appetite in children with CKD worsens with lower ieGFR and is correlated with clinical outcomes, including hospitalizations and quality of life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.