ArticleScientific reports2016
Bio-Source of di-n-butyl phthalate production by filamentous fungi.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 45 citations in OpenAlex.
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- Dibutyl phthalate released by solitary female locusts mediates sexual communication at low density.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Determinants of exposure to endocrine disruptors following hurricane Harvey.Environmental research · 2023Article
- First Data on PAE Levels in Surface Water in Lakes of the Eastern Coast of Baikal.International journal of environmental research and public health · 2023Article
- Bioactivities and Mode of Actions of Dibutyl Phthalates and Nocardamine fromMolecules (Basel, Switzerland) · 2022Article
- Review
- Bioactive Compounds from Marine Sponges: Fundamentals and Applications.Marine drugs · 2021Review
- Detection of Endogenous Phthalates in Bacterial Pathogens of Plants and Animals.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2019Article
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although DBP (di-n-butyl phthalate) is commonly encountered as an artificially-synthesized plasticizer with potential to impair fertility, we confirm that it can also be biosynthesized as microbial secondary metabolites from naturally occurring filamentous fungi strains cultured either in an artificial medium or natural water. Using the excreted crude enzyme from the fungi for catalyzing a variety of substrates, we found that the fungal generation of DBP was largely through shikimic acid pathway, which was assembled by phthalic acid with butyl alcohol through esterification. The DBP production ability of the fungi was primarily influenced by fungal spore density and incubation temperature. This study indicates an important alternative natural waterborne source of DBP in addition to artificial synthesis, which implied fungal contribution must be highlighted for future source control and risk management of DBP.
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Registered trials
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