Observational studyJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2016
Long-Term Survival After Complications Following Major Abdominal Surgery.
Observational study in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06030804 (Impact of Perioperative Dexmedetomidine on Long-term Survival in Older Patients After Cancer Surgery), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Perioperative Dexmedetomidine on Long-term Survival in Older Patients After Cancer Surgery: a Multicenter Randomized Trial
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Multimodal prehabilitation and postoperative outcomes in upper abdominal surgery: systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Effects of intraoperative positive end-expiratory pressure optimization on respiratory mechanics and the inflammatory response: a randomized controlled trial.Journal of clinical monitoring and computing · 2021Trial
- Reduced Long-Term Survival After Postoperative Complications in Major Gastrointestinal Surgery.Therapeutics and clinical risk management · 2025Article
- Complications After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy - Can We Do Better?Journal of surgical oncology · 2024Review
- A retrospective observational study evaluating the association between vasoactive-inotropic score and mortality after major abdominal surgery.Scientific reports · 2024Observational
- Risk factors for death from other diseases after curative gastrectomy and lymph node dissection for gastric cancer.BMC surgery · 2024Article
- Association between compliance with enhanced recovery after surgery (ERAS) protocols and postoperative outcome in patients with primary liver cancer undergoing hepatic resection.Journal of cancer research and clinical oncology · 2022Article
- Long-Term Survival Impact of High-Grade Complications after Liver Resection for Hepatocellular Carcinoma: A Retrospective Single-Centre Cohort Study.Medicina (Kaunas, Lithuania) · 2022Article
- Acute kidney injury following major emergency abdominal surgery - a retrospective cohort study based on medical records data.BMC nephrology · 2022Article
- Hospital Costs and Long-term Survival of Patients Enrolled in an Enhanced Recovery Program for Open Liver Resection: Prospective Randomized Controlled Trial.JMIR perioperative medicine · 2021Article
- Article
- Article
- The association of early postoperative lactate levels with morbidity after elective major abdominal surgery.Bosnian journal of basic medical sciences · 2019Observational
- Long-term impact of postoperative pneumonia after curative gastrectomy for elderly gastric cancer patients.Annals of gastroenterological surgery · 2018Article
- Impact of Intraoperative Blood Transfusions on Survival Rates in Ovarian Cancer Patients.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPostoperative complications have been associated with decreased long-term survival in cardiac, orthopedic, and vascular surgery. For major abdominal surgery research, conflicting evidence is reported in smaller studies. The aim of this study was to assess the effect of complications on long-term survival in major abdominal surgery. MATERIAL AND
methodsAn observational cohort study was conducted of 861 consecutive patients that underwent major abdominal surgery between January 2009 and March 2014, with prospective assessment of the survival status. The effect of postoperative complications on survival was assessed.
resultsPostoperative complications were associated with decreased survival, even after applying correction for 30-day mortality (p < 0.001). Stratified Cox regression analysis depicted postoperative complications to be an important predictor for survival in upper gastrointestinal and female hepatopancreaticobiliary patients. Correction was applied for age, gender, BMI, ASA classification, radicality, and positive lymph node status.
conclusionThese results further indicate the importance of prevention and early diagnosis and treatment of complications. Etiological factors are believed to be both sustained levels of inflammatory markers, as well as attenuated immune response in malignancy with subsequent cancer cell seeding. Future research should aim to prevent and early diagnose postoperative complications to prevent morbidity and mortality not only in the early postoperative phase, but also in the long term.
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