Evidence map›Paper›PMID 26856967›Full record

ArticleJournal of viral hepatitis2016

The Hepatitis C virus treatment cascade at an urban postincarceration transitions clinic.

L Hawks, B L Norton, C O Cunningham, A D Fox

Abstract read
In one paragraph

Article in Journal of viral hepatitis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Hepatitis C Cascades: Data to Inform Hepatitis C Elimination in the United States.Public health reports (Washington, D.C. : 1974) · 2023
    Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

L HawksDepartment of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
B L NortonDepartment of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
C O CunninghamDepartment of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
A D FoxDepartment of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.

Funding

Immunology/Pathology CoreP30AI051519 · NIAID · YESHIVA UNIVERSITY · PI BERMAN, JOAN WEINBERGER · 2003 to 2013
$18.6M
HIV and Substance Abuse Clinical Addiction Research and Education (CARE) ProgramR25DA023021 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ARNSTEN, JULIA H. · 2007 to 2014
$2.7M
Adaptation and testing of a primary care HCV group medical treatment interventionK23DA039060 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI NORTON, BRIANNA · 2015 to 2019
$948k
Buprenorphine Facilitated Access and Supportive Treatment in Former InmatesK23DA034541 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI FOX, AARON D · 2012 to 2016
$913k
Mentoring researchers on drug abuse and HIVK24DA036955 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CUNNINGHAM, CHINAZO · 2014 to 2019
$911k
Resilience in HIV infected drug usersR03DA039727 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CUNNINGHAM, CHINAZO · 2016 to 2017
$167k
NIAID NIH HHS P30 AI051519NIDA NIH HHS K23 DA034541NIDA NIH HHS K23 DA039060NIDA NIH HHS K24 DA036955NIDA NIH HHS R03 DA039727NIDA NIH HHS R25 DA023021
6 · The paper itself

Abstract

Transitions clinics, which provide medical care to individuals who have been released from incarceration, reach a population at high risk for hepatitis C Virus (HCV) infection. We used the HCV treatment cascade to describe HCV care at an urban postincarceration transitions clinic, identifying gaps in care and determining reasons for lapses in care. In this retrospective cohort study, we reviewed electronic health records for all formerly incarcerated individuals receiving care at the Bronx Transitions Clinic. HCV treatment cascade measures included the following: detection of HCV antibodies, confirmation of chronic infection, specialist referral, specialist evaluation, initiation of treatment, completion of treatment and achievement of SVR. We recorded reasons for lapses in care. Of 451 patients accessing care, 317 (70%) were screened for HCV antibodies, and 106 (33%) tested positive. Of the 106 antibody-positive patients, 93 (88%) were evaluated for HCV viremia and 84 (79%) were confirmed to have chronic HCV infection; 19% of the total sample had chronic HCV infection. Of these 84 with chronic HCV, 48 (57%) received specialist referral, 30 (36%) were evaluated, 8 (10%) initiated treatment, and 5 (6%) completed treatment and achieved SVR. Some treatment lapses occurred because patients were deemed unstable for treatment (12%) or were re-incarcerated (5%). Chronic HCV infection was common among transitions clinic patients. Few were treated and cured. Patients lost contact with providers before consideration for antiviral therapy. Referral to specialty providers was a gap in care. Increasing HCV treatment in this population will likely require intensive delivery models.

Indexed as

Health Services ResearchPrisonsAntiviral AgentsFemaleHepatitis C, ChronicHumansMaleMiddle AgedNew York CityRetrospective StudiesTransitional CareAntiviral Agentscascade of carehepatitis Cincarcerationtransitions clinics

Identifiers

PMID26856967
PMCPMC4850086

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.