Evidence map›Paper›PMID 26856843›Full record

ArticleAntimicrobial agents and chemotherapy2016

Molecular Characterization of Escherichia coli Strains Isolated from Retail Meat That Harbor blaCTX-M and fosA3 Genes.

Miaomiao Xie, Dachuan Lin, Kaichao Chen, Edward Wai Chi Chan, Wen Yao, Sheng Chen

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Antibiotics (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Fosfomycin resistance mechanisms inFrontiers in cellular and infection microbiology · 2023
    Review
  6. Effect of high-copper diet on transference ofFrontiers in veterinary science · 2023
    Article
  7. Spread and Molecular Characteristics ofMicrobiology spectrum · 2022
    Article
  8. Article
  9. Article
  10. Plasmid Replicon Typing of Antibiotic-ResistantFrontiers in microbiology · 2020
    Article
  11. Article
  12. Antimicrobial Resistance inMicrobiology spectrum · 2018
    Review
  13. Characteristics of Carbapenem-ResistantFrontiers in microbiology · 2018
    Article
  14. Distribution of ExPEC Virulence Factors,Frontiers in microbiology · 2018
    Article
  15. ESBL-producingFood safety (Tokyo, Japan) · 2017
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Miaomiao XieCollege of Animal Science and Technology, Nanjing Agriculture University, Nanjing, People's Republic of China Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China.
Dachuan LinShenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
Kaichao ChenShenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
Edward Wai Chi ChanShenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
Wen YaoCollege of Animal Science and Technology, Nanjing Agriculture University, Nanjing, People's Republic of China sheng.chen@polyu.edu.hk yaowen67jp@njau.edu.cn.
Sheng ChenShenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong sheng.chen@polyu.edu.hk yaowen67jp@njau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A total of 55 cefotaxime-resistantEscherichia coliisolates were obtained from retail meat products purchased in Shenzhen, China, during the period November 2012 to May 2013. Thirty-seven of these 55 isolates were found to harbor ablaCTX-Mgene, with theblaCTX-M-1group being the most common type.blaCMY-2was detected in 16 isolates, alone or in combination with other extended-spectrum β-lactamase (ESBL) determinants. Importantly, thefosA3gene, which encodes fosfomycin resistance, was detected in 12 isolates, with several being found to reside in the conjugative plasmid that harbored theblaCTX-Mgene. The insertion sequence IS26was observed upstream of some of theblaCTX-M-55andfosA3genes. Conjugation experiments showed thatblaCTX-Mgenes from 15 isolates were transferrable, with Inc I1 and Inc FII being the most prevalent replicons. High clonal diversity was observed among theblaCTX-Mproducers, suggesting that horizontal transfer of theblaCTX-Mgenes amongE. colistrains in retail meats is a common event and that such strains may constitute an important reservoir ofblaCTX-Mgenes, which may be readily disseminated to other potential human pathogens.

Indexed as

AnimalsAnti-Bacterial Agentsbeta-LactamasesChickensChinaConjugation, GeneticDrug Resistance, Multiple, BacterialEscherichia coliEscherichia coli ProteinsFosfomycinGene ExpressionHumansIsoenzymesMeatMicrobial Sensitivity TestsMultilocus Sequence TypingAnti-Bacterial Agentsbeta-lactamase CTX-M, E colibeta-LactamasesEscherichia coli ProteinsFosA(3) protein, E coliFosfomycinIsoenzymes

Identifiers

PMID26856843
PMCPMC4808224

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.