ArticleJournal of medical toxicology : official journal of the American College of Medical Toxicology2016
Two Cases of Refractory Cardiogenic Shock Secondary to Bupropion Successfully Treated with Veno-Arterial Extracorporeal Membrane Oxygenation.
Article in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 49 citations in OpenAlex.
- Inhaled sevoflurane use for myoclonic status secondary to bupropion intoxication.Critical care science · 2025Article
- Combined lipid emulsion and plasma exchange in massive pediatric bupropion overdose: Case Report.Frontiers in toxicology · 2025Article
- Predicting adverse cardiovascular events in emergency department patients with bupropion overdose.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2024Article
- A bupropion modulatory site in the Gloeobacter violaceus ligand-gated ion channel.Biophysical journal · 2024Article
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- Identification of a binding site for bupropion inbioRxiv : the preprint server for biology · 2023Article
- Use of Multimodal Mechanical Support in Refractory Cardiogenic Shock From Bupropion Overdose.Cureus · 2023Article
- BUPROPION MISUSE BY NASAL INSUFFLATION WITH A FATAL OUTCOME: CASE REPORT AND REVIEW.Actas espanolas de psiquiatria · 2023Article
- Seizure and Other Catastrophes due to Bupropion Overdose: Recent Case Report and Review of Published Cases.Innovations in clinical neuroscience · 2023Article
- Toxicologic Confounders of Brain Death Determination: A Narrative Review.Neurocritical care · 2021Review
- Perioperative Considerations for Patients With Major Depressive Disorder Undergoing Surgery.Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses · 2020Article
- Successful Management of Adolescent Bupropion Overdose with Intravenous Lipid Emulsion Therapy.Journal of pediatric intensive care · 2019Article
- Cardiac arrest induced by the intentional ingestion of boric acid and mirtazapine treated by percutaneous cardiopulmonary bypass: a case report.Journal of medical case reports · 2019Article
- Local Anesthetic Systemic Toxicity Induced Cardiac Arrest After Topicalization for Transesophageal Echocardiography and Subsequent Treatment With Extracorporeal Cardiopulmonary Resuscitation.Journal of cardiothoracic and vascular anesthesia · 2019Article
- Reviewing the Record: Medical Record Reviews for Medical Toxicology Research.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2018Article
- Examining the role of extracorporeal membrane oxygenation in patients following suspected or confirmed suicide attempts: A case series.Journal of critical care · 2018Article
- Coma with Absent Brainstem Reflexes and Burst Suppression after Bupropion Overdose in a Child.Neurocritical care · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bupropion inhibits the uptake of dopamine and norepinephrine. Clinical effects in overdose include seizure, status epilepticus, tachycardia, arrhythmias, and cardiogenic shock. We report two cases of severe bupropion toxicity resulting in refractory cardiogenic shock, cardiac arrest, and repeated seizures treated successfully. Patients with cardiovascular failure related to poisoning may particularly benefit from extracorporeal membrane oxygenation (ECMO). These are the first cases of bupropion toxicity treated with veno-arterial EMCO (VA-ECMO) in which bupropion toxicity is supported by confirmatory testing. Both cases demonstrate the effectiveness of VA-ECMO in poisoned patients with severe cardiogenic shock or cardiopulmonary failure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.