ArticleScientific reports2016
Constitutive expression of a novel antimicrobial protein, Hcm1, confers resistance to both Verticillium and Fusarium wilts in cotton.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Genome-Wide Identification Analysis of the MAPKKK Gene Family in Cotton and Its Role in Development and Stress Response.International journal of molecular sciences · 2026Article
- Viral vectors for antimicrobial peptide expression: a new path for crop protection.Frontiers in microbiology · 2026Review
- Fatty Acid ABCG TransporterPlants (Basel, Switzerland) · 2025Article
- Hen Egg White Lysozyme (HEWL) Confers Resistance to Verticillium Wilt in Cotton by Inhibiting the Spread of Fungus and Generating ROS Burst.International journal of molecular sciences · 2023Article
- CottonBiology · 2023Article
- Strigolactones positively regulate Verticillium wilt resistance in cotton via crosstalk with other hormones.Plant physiology · 2023Article
- The effects and interrelationships of intercropping on Cotton Verticillium wilt and soil microbial communities.BMC microbiology · 2023Article
- Transcriptomic analysis of bakanae disease resistant and susceptible rice genotypes in response to infection by Fusarium fujikuroi.Molecular biology reports · 2022Article
- Membrane Localized GbTMEM214s Participate in Modulating Cotton Resistance to Verticillium Wilt.Plants (Basel, Switzerland) · 2022Article
- The barley leaf rust resistance gene Rph3 encodes a predicted membrane protein and is induced upon infection by avirulent pathotypes of Puccinia hordei.Nature communications · 2022Article
- Lauric Acid Induces Apoptosis of Rice Sheath Blight Disease Caused byJournal of fungi (Basel, Switzerland) · 2022Article
- Integrative transcriptomic and gene co-expression network analysis of host responses upon Verticillium dahliae infection in Gossypium hirsutum.Scientific reports · 2021Article
- Ergosterol-targeting fusion antifungal peptide significantly increases the Verticillium wilt resistance of cotton.Plant biotechnology journal · 2021Article
- CGTase, a novel antimicrobial protein from Bacillus cereus YUPP-10, suppresses Verticillium dahliae and mediates plant defence responses.Molecular plant pathology · 2021Article
- Transcriptomic analysis of gene expression of Verticillium dahliae upon treatment of the cotton root exudates.BMC genomics · 2020Article
- Quantitative Trait Locus Mapping and Candidate Gene Analysis forFrontiers in plant science · 2018Article
- Article
- Overexpression of SSBFrontiers in plant science · 2018Article
- A transient transformation system for gene characterization in upland cotton (Plant methods · 2018Article
- ghr-miR5272a-mediated regulation of GhMKK6 gene transcription contributes to the immune response in cotton.Journal of experimental botany · 2017Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Fusarium and Verticillium wilts, two of the most important diseases in cotton, pose serious threats to cotton production. Here we introduced a novel antimicrobial protein Hcm1, which comprised harpin protein from Xanthomonas oryzae pv. oryzicola (Xoc), and the chimeric protein, cecropin A-melittin, into cotton. The transgenic cotton lines with stable Hcm1 expression showed a higher resistance to Verticillium and Fusarium wilts both in greenhouse and field trials compared to controls. Hcm1 enabled the transgenic cotton to produced a microscopic hypersensitive response (micro-HR), reactive oxygen species (ROS) burst, and caused the activation of pathogenesis-related (PR) genes in response to biotic stress, indicating that the transgenic cotton was in a primed state and ready to protect the host from pathogenic infection. Simultaneously, Hcm1 protein inhibited the growth of Verticillium dahliae (V. dahliae) and Fusarium oxysporum (F. oxysporum) in vitro. The spread of fungal biomass was also inhibited in vivo since the V. dahliae biomass was decreased dramatically in transgenic cotton plants after inoculation with V. dahliae. Together, these results demonstrate that Hcm1 could activate innate immunity and inhibit the growth of V. dahliae and F. oxysporum to protect cotton against Verticillium and Fusarium wilts.
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