Evidence map›Paper›PMID 26856123›Full record

ArticleJournal of palliative care2015

Pain Symptoms Associated with Opioid Use among Vulnerable Persons with HIV: An exploratory study with implications for palliative care and opioid abuse prevention.

Amy R Knowlton, Trang Q Nguyen, Allysha C Robinson, Paul T Harrell, Mary M Mitchell

Open access · greenAbstract read
In one paragraph

Article in Journal of palliative care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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  15. Chronic Pain in HIV.Molecular pain
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Amy R Knowlton
Trang Q Nguyen
Allysha C Robinson
Paul T Harrell
Mary M Mitchell
Johns Hopkins University · USBrigham and Women's Hospital · USMoffitt Cancer Center · US

Funding

NIDA Epidemiology Training Program: Johns Hopkins UniversityT32DA007292 · NIDA · JOHNS HOPKINS UNIVERSITY · PI RENEE M. JOHNSON, Brion S Maher · 1993 to 2026
$17.7M
Sustaining palliative care to drug users with HIV/AIDS & health disparitiesR01NR014050 · NINR · JOHNS HOPKINS UNIVERSITY · PI KNOWLTON, AMY · 2013 to 2017
$2.3M
Informal Caregiving & Medical Adherence Among HIV+ IDUsR01DA019413 · NIDA · JOHNS HOPKINS UNIVERSITY · PI KNOWLTON, AMY · 2006 to 2009
$2.2M
NIDA NIH HHS R01 DA019413NIDA NIH HHS T32 DA007292NINR NIH HHS R01 NR014050
6 · The paper itself

Abstract

Current or former injection drug users with human immunodeficiency virus (HIV) are at high risk for pain, which adversely affects their quality of life and may increase their risk for illicit drug use or relapse. We explored associations between pain symptoms and substance use among injection-drug-using study participants with HIV who had histories of heroin use. Using generalized estimating equations and controlling for prior substance use, we found that pain in each six-month period was associated with the use of heroin and prescription opioids, but not the use of nonopioid drugs or alcohol. Routine clinical assessment and improved management of pain symptoms may be needed for persons with HIV and a history of injection drug use, particularly those with chronic pain, for whom there is increased risk for heroin use.

Indexed as

HIV SeropositivityPalliative CareVulnerable PopulationsAlcohol DrinkingAnalgesics, OpioidChronic PainCocaineFemaleHeroin DependenceHumansMaleMarijuana SmokingMiddle AgedPain ManagementQuality of LifeAnalgesics, OpioidCocaine

Identifiers

PMID26856123
PMCPMC4778742
OpenAlexW2297543143

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.