Towards a scalable HIV cure research agenda: the role of co-infections.

Irini Sereti, Gregory K Folkers, Graeme Meintjes, David R Boulware

Abstract read

In one paragraph

Article in Journal of virus eradication. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Research on HIV cure: Mapping the ethics landscape.PLoS medicine · 2017
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Irini SeretiNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

Gregory K FolkersNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

Graeme MeintjesUniversity of Cape Town, Cape Town, South Africa; Imperial College London, London, UK.

David R BoulwareUniversity of Minnesota, Minneapolis, Minnesota.

Funding

Immunopathogenic Mechanisms of Human Immunodeficiency Virus (HIV) DiseaseZIAAI001121 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SERETI, IRINI · 2010 to 2025

$27.2M

Intramural NIH HHS Z99 AI999999

6 · The paper itself

Abstract

The development of a cure is among the foremost contemporary priorities in the field of HIV research. The science that underpins a potential HIV cure should be generalisable to the many millions of persons globally who enter antiretroviral treatment programs with advanced immunosuppression and/or an opportunistic infection. We provide five key suggestions for incorporation into the HIV cure research agenda to maximise the generalisability and applicability of an HIV cure once developed.

Indexed as

AIDSHIVHIV cureopportunistic infections

Identifiers

PMID26855972

PMCPMC4739889

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.