ArticleTranslational vision science & technology2016
Three-Year Efficacy and Safety of a Silicone Oil-Filled Foldable-Capsular-Vitreous-Body in Three Cases of Severe Retinal Detachment.
Article in Translational vision science & technology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Foldable capsular vitreous body indications, complications, and outcomes: a systematic review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Pooled it
- Timing of intravitreal foldable capsular vitreous body implantation after silicone oil tamponade.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- The efficacy of intraoperative OCT combined with foldable artificial vitreous balloon (FCVB) implantation in eyes with complex retinal detachment and silicone oil dependence.BMC ophthalmology · 2025Article
- Consensus on the Treatment of Severe Ocular Trauma and Silicone Oil-Dependent Eyes Using Foldable Capsular Vitreous Body.Journal of evidence-based medicine · 2025Article
- Precise prediction of size of a foldable capsular vitreous body via computerized three-dimensional ocular reconstruction in severe retinal detachment.BMC ophthalmology · 2024Article
- Efficacy of Foldable Capsular Vitreous Body Implants Filled With Light or Heavy Silicone Oil in the Treatment of Silicone Oil-dependent Eyes.Translational vision science & technology · 2024Article
- Study on maintenance of eyeball morphology by foldable capsular vitreous body in severe ocular trauma.BMC ophthalmology · 2023Article
- Clinical Efficacy and Safety of Foldable Capsular Vitreous Body Implant Surgery in 22 Cases of Silicone Oil-dependent Eyes.Current medical science · 2023Article
- Advances in Polysaccharide- and Synthetic Polymer-Based Vitreous Substitutes.Pharmaceutics · 2023Review
- Study on the efficacy and safety of foldable capsular vitreous body in the severe retinal detachment eyes.BMC ophthalmology · 2022Article
- Clinical Application of Foldable Capsular Vitreous Bodies in the Treatment of Severe Ocular Trauma and Silicone Oil Dependent Eyes.Journal of ophthalmology · 2022Article
- Reattachment After Foldable Capsular Vitreous Body Implantation in Severe Retinal Detachment Eyes.Translational vision science & technology · 2021Article
- Foldable capsular vitreous body implantation for treatment of traumatic retinal detachment: two case reports.The Journal of international medical research · 2021Article
- Evaluation of the long-term effect of foldable capsular vitreous bodies in severe ocular rupture.International journal of ophthalmology · 2021Article
- Study on the effectiveness and safety of Foldable Capsular Vitreous Body implantation.BMC ophthalmology · 2019Article
- Risk Factors for Trauma-Related Eviscerations: Analysis of 821 Cases.Journal of ophthalmology · 2019Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe previously designed a novel foldable capsular vitreous body (FCVB) to treat severe retinal detachment and evaluated its performance in a 1-year follow up study. The purpose of this study was to determine the efficacy and safety of a silicone oil (SO)-filled FCVB in a 3-year follow-up.
methodsStandard three-port pars plana vitrectomy was performed, and the FCVB was triple folded and implanted in the vitreous cavity of three eyes. The SO then was injected into the capsule to support the retina. The eyes were examined using Goldmann applanation tonometry, fundus photography, optical coherence tomography (OCT), noncontact specular microscopy, and ultrasound biomicroscopy over a 3-year implantation period.
resultsAt the 3-year follow-up, retinal reattachment was achieved in all three cases, with steady intraocular pressure. The visual acuity showed slight fluctuations, and it was slightly increased compared to baseline. Optical coherence tomography revealed decreased retinal thickness and an altered retinal structure in the implanted eyes compared to the control eyes. No keratopathy, glaucoma, SO leakage, SO emulsification, or other apparent complications occurred during the observation period.
conclusionThe SO-filled FCVB was effective and safe as a vitreous substitute in three eyes over a 3-year observation period. TRANSLATIONAL RELEVANCE: Silicone oil emulsification is a severe complication after retinal detachment surgery. On the basis of animal experiments, we investigated a new strategy and product, the FCVB, to overcome this complication. In this pilot study, FCVB limited SO emulsification and migration. This study could lay the foundation for a further multicenter clinical trial.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.