Evidence map›Paper›PMID 26855802›Full record

ArticleCentral European journal of urology2015

Repair of a vesico-vaginal fistula with amniotic membrane - Step 1 of the IDEAL recommendations of surgical innovation.

Dimitri Barski, Holger Gerullis, Thorsten Ecke, Gabriella Varga, Mihaly Boros, Isabel Pintelon, Jean-Pierre Timmermans, Alexander Winter, Jens-Willem Bagner, Thomas Otto

2 registry-linked trialsAbstract read
In one paragraph

Article in Central European journal of urology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03864939 phase2 / phase3unknown statusnot on this mapstarted 2019, after this paper: background citation

Randomized Pilot Study to Improve Postprostatectomy Incontinence and Potency by Application of Dried Human Amnion Graft

TypeinterventionalSponsorGerman Centre for Assessment and Evaluation of Innovative Techniques in MedicineRan2019 to 2025Enrolled328ConditionsContinence, Potency, Complication, Biochemical RecurrenceArmsdHAM, No dHAM
NCT03891225 phase1completednot on this mapstarted 2019, after this paper: background citation

Efficacy of Amniotic Membrane Implantation Over Pancreo-jejunal Anastomosis After Pancreaticoduodenectomy in Reducing Post-operative Pancreatic Fistula POPF.

TypeinterventionalSponsorCasa di Cura Dott. PederzoliRan2019 to 2020Enrolled20ConditionsPost Operative Pancreatic Fistula, Pancreatic Resection, Biological DressingArmsAmniotic Membrane implantation
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Biological properties and surgical applications of the human amniotic membrane.Frontiers in bioengineering and biotechnology · 2022
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dimitri BarskiDepartment of Urology, Lukas Hospital Neuss, Germany.
Holger GerullisDepartment of Urology, Lukas Hospital Neuss, Germany.
Thorsten EckeDepartment of Urology, HELIOS Hospital, Bad Saarow, Germany.
Gabriella VargaInstitute of Experimental Surgery, University of Szeged, Hungary.
Mihaly BorosInstitute of Experimental Surgery, University of Szeged, Hungary.
Isabel PintelonUniversity of Antwerp, Laboratory of Cell Biology and Histology, Antwerp, Belgium.
Jean-Pierre TimmermansUniversity of Antwerp, Laboratory of Cell Biology and Histology, Antwerp, Belgium.
Alexander WinterUniversity Hospital for Urology, School of Medicine and Health Sciences, Carl von Ossietzky University, Oldenburg, Germany.
Jens-Willem BagnerDepartment of Urology, Lukas Hospital Neuss, Germany.
Thomas OttoDepartment of Urology, Lukas Hospital Neuss, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionComplex vesico-vaginal fistula (VVF) has a high recurrence rate and so the repair with graft tissues seems to be favorable. Amniotic membrane (AM) plays an increasing role as a scaffold for the repair of defect tissue due to its unique biological properties with regard to promoting wound healing. MATERIAL AND

methodsAn innovative surgical procedure for AM-assisted repair of a complex vesico-vaginal fistula as the Idea Stage following the IDEAL recommendations is presented. The development of amnion preparation and the involved surgical steps are described.

resultsWe are able to report a successful repair of VVF by abdominal approach with an amniotic membrane graft. Good functional results, no adverse events and no graft rejection have been detected.

conclusionsFavorable results confirm the technical simplicity, safety and efficacy of this procedure. Following the IDEAL recommendations, consecutive animal experiments and a cohort study are in progress.

Indexed as

amniotic membraneIDEAL recommendationsvesico-vaginal fistula

Identifiers

PMID26855802
PMCPMC4742445

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.