ArticleCentral European journal of urology2015
Durability, safety and efficacy of polyacrylamide hydrogel (Bulkamid(®)) in the management of stress and mixed urinary incontinence: three year follow up outcomes.
Article in Central European journal of urology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Adverse Events Associated with Nonsurgical Treatments for Urinary Incontinence in Women: a Systematic Review.Journal of general internal medicine · 2019Pooled it
- Trial
- Hydrogel-Based Therapies for Female Stress Urinary Incontinence: From Bulking Agents to Regenerative Platforms-A Narrative Review.Current urology reports · 2026Review
- Modern Conservative Management Strategies for Female Stress Urinary Incontinence: A Systematic Review.Journal of clinical medicine · 2025Review
- In vivo biocompatibility and long-term durability of nanofibrillated cellulose as a urethral bulking agent in rats and Beagle dogs.PloS one · 2025Article
- Could infiltration anesthesia decrease anchor-fixation quality of midurethral slings in the obturator complex?International urogynecology journal · 2023Article
- Long-term outcomes of polyacrylamide hydrogel treatment in women with stress urinary incontinence.BJU international · 2022Article
- Hydrogels for Tissue Engineering: Addressing Key Design Needs Toward Clinical Translation.Frontiers in bioengineering and biotechnology · 2022Review
- Combination therapy with botulinum toxin and bulking agent-An efficient, sustainable, and safe method to treat elderly women with mixed urinary incontinence.Neurourology and urodynamics · 2021Article
- Urethral bulking agents: a retrospective review of primary versus salvage procedure outcomes.World journal of urology · 2021Article
- Seven-year efficacy and safety outcomes of Bulkamid for the treatment of stress urinary incontinence.Neurourology and urodynamics · 2021Article
- Particulate Versus Non-Particulate Bulking Agents In The Treatment Of Stress Urinary Incontinence.Research and reports in urology · 2019Review
- Functional Outcome of Human Adipose Stem Cell Injections in Rat Anal Sphincter Acute Injury Model.Stem cells translational medicine · 2018Article
- Bulkamid (PAHG) in mixed urinary incontinence: What is the outcome?International urogynecology journal · 2017Article
- A national population-based cohort study of urethral injection therapy for female stress and mixed urinary incontinence: the Danish Urogynaecological Database, 2007-2011.International urogynecology journal · 2017Article
- The Efficacy of Polyacrylamide Hydrogel (Bulkamid) Transurethral Injection System: The Outcome of Short-term Follow-up of 100 Cases.Gynecology and minimally invasive therapyArticle
- Effectiveness and safety of polyacrylamide hydrogel injection for female stress urinary incontinence: A systematic review and single-arm meta-analysis.Indian journal of urology : IJU : journal of the Urological Society of IndiaReview
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThere are a myriad of treatment options available for patients suffering with the increasingly prevalent condition of stress urinary incontinence (SUI). The minimally invasive nature of periurethral bulking agents makes them an attractive proposition in the correctly selected patient. There is, however, limited data available on the medium to long term safety and efficacy of this procedure. The aim of our study is to evaluate the outcomes of Polyacrylamide Hydrogel (PAHG) (Bulkamid(®)) as a periurethral bulking agent at our institution. MATERIAL AND
methodsFrom 2006 to 2011, two hundred and fifty six women underwent periurethral bulking with PAHG in the management of SUI or mixed urinary incontinence (MUI). Women were assessed with at least yearly quality of life and ICIQ questionnaires.
resultsThe majority of patients had the procedure under a local anaesthetic, with a median operative time of 9 minutes. Median follow up was 38 months. 82% of patients reported cure/significant improvement at 3 months. Importantly, this high satisfaction rate was maintained at final follow up and was reflected in both VAS and ICIQ scores. There were no reported adverse reactions and no significant safety concerns.
conclusionsWe conclude that Bulkamid(®) injection is an efficacious, minimally invasive, and safe procedure for a selected group of patients with stress incontinence. In our study, PAHG has been shown to be durable and safe.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.