Evidence map›Paper›PMID 26855782›Full record

ArticleBasic and clinical andrology2016

Anabolic steroids abuse and male infertility.

Rabih El Osta, Thierry Almont, Catherine Diligent, Nicolas Hubert, Pascal Eschwège, Jacques Hubert

Open access · goldAbstract read
In one paragraph

Article in Basic and clinical andrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 119 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Nonobstructive azoospermia: an etiologic review.Asian journal of andrology · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Sustanon suppresses spermatogenesis and increases cell death.Translational andrology and urology · 2024
    Article
  16. Impacts of Anabolic-androgenic steroid supplementation on female health and offspring: Mechanisms, side effects, and medical perspectives.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Review
  17. Article
  18. Review
  19. The assessment of liver function test and fertility hormones in Saudi athletes using anabolic androgenic steroids.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rabih El OstaUrology Department of Brabois University Hospital, CHU de Nancy, Allée du Morvan, 54511 Vandœuvre les Nancy, France.
Thierry AlmontEA3694 Human Fertility Research Group, CHU Paule de Viguier, TSA 70034, 31059 Toulouse cedex 9, France.
Catherine DiligentLaboratory of reproductive biology, CHU de Nancy, 10 rue du Dr Heydenreich, 54042 Nancy, France.
Nicolas HubertUrology Department of Brabois University Hospital, CHU de Nancy, Allée du Morvan, 54511 Vandœuvre les Nancy, France.
Pascal EschwègeUrology Department of Brabois University Hospital, CHU de Nancy, Allée du Morvan, 54511 Vandœuvre les Nancy, France.
Jacques HubertUrology Department of Brabois University Hospital, CHU de Nancy, Allée du Morvan, 54511 Vandœuvre les Nancy, France.
Centre Hospitalier Régional et Universitaire de Nancy · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For several decades, testosterone and its synthetic derivatives have been used with anabolic and androgenic purposes. These substances were first restricted to professional bodybuilders, but become more and more popular among recreational athletes. Up to date, 3,000,000 anabolic-androgenic steroids (AAS) users have been reported in the United States with an increasing prevalence, making AAS consumption a major public health growing concern. Infertility is defined by the WHO as the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse and a male factor is present in up to 50 % of all infertile couples. Several conditions may be related to male infertility. Substance abuse, including AAS, is commonly associated to transient or persistent impairment on male reproductive function, through different pathways. Herein, a brief overview on AAS is offered. Steroids biochemistry, patterns of use, physiological and clinical issues are enlightened. A further review about fertility outcomes among male AAS abusers is also presented, including the classic reports on transient anabolic steroid-induced hypogonadism (ASIH), and the more recent experimental reports on structural and genetic sperm damage.

Indexed as

Anabolic androgenic steroidsHypogonadismMale infertility

Identifiers

PMID26855782
PMCPMC4744441
OpenAlexW2269409642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.