ReviewJournal of clinical and experimental dentistry2016
Antimicrobial effects of Citrus sinensis peel extracts against dental caries bacteria: An in vitro study.
Review in Journal of clinical and experimental dentistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The trial behind it
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Who cites it
33 citing papers in PubMed, 122 citations in OpenAlex.
- Recovery of bioactive compounds from citrus by-products: advances in conventional and innovative extraction approaches, bioavailability, and applications.BMC chemistry · 2026Review
- Antibacterial activity of orange peel extractOpen veterinary journal · 2025Article
- Exploring the In Vitro Anti-Inflammatory Effect of Citrus Fruit Hesperidin Supplementation.Food science & nutrition · 2025Article
- Anticariogenic effect of herbal extracts and other commercial products againstJournal of conservative dentistry and endodontics · 2025Article
- Medicinal Plants Against Dental Caries: Research and Application of Their Antibacterial Properties.Plants (Basel, Switzerland) · 2025Review
- Antimicrobial activities of biosynthesized nanosilver using Musa paradisiaca and Citrus sinensis peel extracts against major human and plant pathogens.Scientific reports · 2025Article
- Production of Prophylactic Nanoformulation for Dental Caries and Investigation of Its Effectiveness by In Vitro and In Silico Methods.Pharmaceutics · 2025Article
- Optimizing processing methods for maximum bioactive retention: comparative metabolomic analysis of dried loquat (Frontiers in nutrition · 2025Article
- Comparative Evaluation of Locally Applied Chlorhexidine 1% Gel andInternational journal of dentistry · 2025Article
- Effect of orange pulp with or without zeolite on productive performance, nitrogen utilization, and antioxidative status of growing rabbits.Tropical animal health and production · 2024Article
- Exploring the therapeutic potential of medicinal plants and their active principles in dental care: A comprehensive review.Heliyon · 2024Review
- Green Methods to Recover Bioactive Compounds from Food Industry Waste: A Sustainable Practice from the Perspective of the Circular Economy.Molecules (Basel, Switzerland) · 2024Review
- Aromatic Plants as Potential Resources to Combat Osteoarthritis.Combinatorial chemistry & high throughput screening · 2024Review
- Antimicrobial Activity ofMedicina (Kaunas, Lithuania) · 2023Article
- The Potential Uses of Baobab Tree's Medicinal Effects in Dentistry: A Literature Review.Cureus · 2023Review
- Revisiting the Therapeutic Effects of Essential Oils on the Oral Microbiome.Pharmacy (Basel, Switzerland) · 2023Review
- A Real-World Scenario of Citizens' Motivation and Engagement in Urban Waste Management Through a Mobile Application and Smart City Technology.Circular economy and sustainability · 2023Article
- In vitro antibacterial and antifungal activities of extracts and fractions of leaves of Ricinus communis Linn against selected pathogens.Veterinary medicine and science · 2022Article
- Phytochemical Screening and In Vitro Antifungal Activity of Selected Medicinal Plants againstAdvances in pharmacological and pharmaceutical sciences · 2022Article
- Antidiabetic Activity of Hydromethanolic Extract of CrudeJournal of experimental pharmacology · 2022Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEthnomedicine is gaining admiration since years but still there is abundant medicinal flora which is unrevealed through research. The study was conducted to assess the in vitro antimicrobial potential and also determine the minimum inhibitory concentration (MIC) of Citrus sinensis peel extracts with a view of searching a novel extract as a remedy for dental caries pathogens. MATERIAL AND
methodsAqueous and ethanol (cold and hot) extracts prepared from peel of Citrus sinensis were screened for in vitro antimicrobial activity against Streptococcus mutans and Lactobacillus acidophilus, using agar well diffusion method. The lowest concentration of every extract considered as the minimal inhibitory concentration (MIC) values were determined for both test organisms. One way ANOVA with Post Hoc Bonferroni test was applied for statistical analysis. Confidence level and level of significance were set at 95% and 5% respectively.
resultsDental caries pathogens were inhibited most by hot ethanolic extract of Citrus sinensispeel followed by cold ethanolic extract. Aqueous extracts were effective at very high concentrations. Minimum inhibitory concentration of hot and cold ethanolic extracts of Citrus sinensis peel ranged between 12-15 mg/ml against both the dental caries pathogens.
conclusionsCitrus sinensispeels extract was found to be effective against dental caries pathogens and contain compounds with therapeutic potential. Nevertheless, clinical trials on the effect of these plants are essential before advocating large-scale therapy. KEY WORDS: Agar well diffusion, antimicrobial activity, dental caries, Streptococcus mutans, Lactobacillus acidophilus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.