Evidence map›Paper›PMID 26855573›Full record

ReviewInternational journal of nanomedicine2016

Impact of single-walled carbon nanotubes on the embryo: a brief review.

Ala-Eddin Al Moustafa, Etienne Mfoumou, Dacian E Roman, Vahe Nerguizian, Anas Alazzam, Ion Stiharu, Amber Yasmeen

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 4 countries.

Ala-Eddin Al MoustafaCollege of Medicine & Biomedical Research Centre, Qatar University, Doha, Qatar; Oncology Department, McGill University, Montreal, QC, Canada; Mechanical and Industrial Engineering Department, Concordia University, Montreal, QC, Canada; Syrian Research Cancer Centre of the Syrian Society against Cancer, Aleppo, Syria.
Etienne MfoumouNova Scotia Community College, Dartmouth, NS, Canada.
Dacian E RomanMechanical and Industrial Engineering Department, Concordia University, Montreal, QC, Canada.
Vahe NerguizianÉcole de Technologie Supérieure, Montreal, QC, Canada.
Anas AlazzamDepartment of Mechanical Engineering, Khalifa University, Abu Dhabi, UAE.
Ion StiharuMechanical and Industrial Engineering Department, Concordia University, Montreal, QC, Canada.
Amber YasmeenSegal Cancer Centre, Lady Davis Institute for Medical Research of the Sir Mortimer B. Davis-Jewish General Hospital, Montreal, QC, Canada.
Concordia University · CAÉcole de Technologie Supérieure · CAJewish General Hospital · CAKhalifa University of Science and Technology · AENova Scotia Community College · CASyrian Center for Tobacco Studies · SY

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

Carbon nanotubes (CNTs) are considered one of the most interesting materials in the 21st century due to their unique physiochemical characteristics and applicability to various industrial products and medical applications. However, in the last few years, questions have been raised regarding the potential toxicity of CNTs to humans and the environment; it is believed that the physiochemical characteristics of these materials are key determinants of CNT interaction with living cells and hence determine their toxicity in humans and other organisms as well as their embryos. Thus, several recent studies, including ours, pointed out that CNTs have cytotoxic effects on human and animal cells, which occur via the alteration of key regulator genes of cell proliferation, apoptosis, survival, cell-cell adhesion, and angiogenesis. Meanwhile, few investigations revealed that CNTs could also be harmful to the normal development of the embryo. In this review, we will discuss the toxic role of single-walled CNTs in the embryo, which was recently explored by several groups including ours.

Indexed as

AnimalsEmbryo, MammalianEnvironmental ExposureHumansNanotubes, CarbonToxicity TestsNanotubes, Carbonembryosingle-walled carbon nanotubestoxicity

Identifiers

PMID26855573
PMCPMC4725643
OpenAlexW2296245842

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.