Evidence map›Paper›PMID 26855485›Full record

ArticleIndian journal of clinical biochemistry : IJCB2016

Idiopathic Fetal Growth Restriction: Repercussion of Modulation in Oxidative Stress.

Nilesh Chandra, Mohit Mehndiratta, B D Banerjee, K Guleria, A K Tripathi

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Indian journal of clinical biochemistry : IJCB, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nilesh ChandraDepartment of Biochemistry, University College of Medical Sciences and G T B Hospital, Dilshad Garden, Delhi, 110095 India.
Mohit MehndirattaDepartment of Biochemistry, University College of Medical Sciences and G T B Hospital, Dilshad Garden, Delhi, 110095 India.
B D BanerjeeDepartment of Biochemistry, University College of Medical Sciences and G T B Hospital, Dilshad Garden, Delhi, 110095 India.
K GuleriaDepartment of Obstetrics & Gynecology, University College of Medical Sciences and G T B Hospital, Dilshad Garden, Delhi, 110095 India.
A K TripathiDepartment of Biochemistry, University College of Medical Sciences and G T B Hospital, Dilshad Garden, Delhi, 110095 India.
University College of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress has been proposed as one of the causes involved in idiopathic fetal growth restriction (IFGR). However, the exact relationship between oxidative stress and IFGR is not understood. This study aimed at understanding the role of oxidative stress and antioxidant status in IFGR materno-fetal dyads and matched controls. 75 materno-fetal dyads with IFGR were enrolled with equal number of normal low risk controls. Malondialdehyde (MDA) levels were measured as marker of oxidative stress, while paraoxonase-1 (PON1) activity and total antioxidant capacity (TAC) of serum were measured as markers of antioxidant status. MDA levels were increased in both maternal and cord blood of IFGR neonates as compared to controls (p < 0.001). TAC of serum were found to be decreased in IFGR (both maternal and cord blood) as compared to controls (p < 0.001; p < 0.05, respectively). PON1 activity was found to be decreased in the IFGR mothers while it was found increased in IFGR cord blood (p < 0.01; p < 0.001)). IFGR is a state of increased oxidative stress. Decreased PON1 enzymatic activity in mothers is also associated with IFGR.

Indexed as

Idiopathic fetal growth restrictionMalondialdehydeOxidative stressParaoxonase-1Total antioxidant capacity

Identifiers

PMID26855485
PMCPMC4731372
OpenAlexW2080999932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.