ArticleJournal of magnetic resonance imaging : JMRI2016
Assessment of renal function using intravoxel incoherent motion diffusion-weighted imaging and dynamic contrast-enhanced MRI.
Article in Journal of magnetic resonance imaging : JMRI, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 48 citations in OpenAlex.
- The role of diffusion-weighted MRI in biological image-guided radiation therapy: a roadmap.Physics in medicine and biology · 2026Review
- Multimodal Magnetic Resonance Imaging in Diabetic Kidney Disease: From Pathophysiological Insights to Clinical Applications.Diagnostics (Basel, Switzerland) · 2026Review
- Cardiac-Gated Diffusion-Weighted Magnetic Resonance Imaging Assessment of Kidney Function in Patients With Kidney Cancer.Kidney international reports · 2026Article
- Streamlined calculation of kidney function using dynamic contrast-enhanced MRI with population-based arterial input function and a whole-kidney model.European radiology experimental · 2026Article
- Quantitative Parameters Derived Using the Biexponential and Stretched Exponential Models for the Detection of Early Renal Impairment in Chronic Kidney Disease.Current medical imaging · 2025Article
- Evaluation of Renal Perfusion: A Comparative Study between Intravoxel Incoherent Motion (IVIM) Imaging and Arterial Spin Labeling (ASL) to Assess Renal Blood Flow in Rodents.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Article
- Grading of clear cell renal cell carcinoma using diffusion MRI with a multimodal apparent diffusion model.Frontiers in oncology · 2025Article
- Tri- and bi-exponential diffusion analyses of the kidney: effect of respiratory-controlled acquisition on diffusion parameters.Radiological physics and technology · 2023Article
- Magnetic Resonance Imaging in Clinical Trials of Diabetic Kidney Disease.Journal of clinical medicine · 2023Review
- Intravoxel incoherent motion diffusion-weighted MRI of renal parenchyma and its clinical significance in patients with untreated acute leukemia: a pilot study.Abdominal radiology (New York) · 2023Article
- Preliminary study on intravoxel incoherent motion imaging and diffusion kurtosis imaging based on magnetic resonance imaging of normal kidneys in children.Translational pediatrics · 2022Article
- Magnetic resonance image compilation sequence to quantitatively detect active sacroiliitis with axial spondyloarthritis.Quantitative imaging in medicine and surgery · 2022Article
- Assessment of kidney function in chronic kidney disease by combining diffusion tensor imaging and total kidney volume.International urology and nephrology · 2022Article
- Intravoxel incoherent motion to differentiate spinal metastasis: A pilot study.Frontiers in oncology · 2022Article
- Noninvasive assessment of kidney dysfunction in children by using blood oxygenation level-dependent MRI and intravoxel incoherent motion diffusion-weighted imaging.Insights into imaging · 2021Article
- Evaluation of Radiographic Contrast-Induced Nephropathy by Functional Diffusion Weighted Imaging.Journal of clinical medicine · 2021Article
- Validation of multiparametric MRI by histopathology after nephrectomy: a case study.Magma (New York, N.Y.) · 2021Article
- Retrospective Distortion and Motion Correction for Free-Breathing DW-MRI of the Kidneys Using Dual-Echo EPI and Slice-to-Volume Registration.Journal of magnetic resonance imaging : JMRI · 2021Article
- Multiparametric Renal MRI: An Intrasubject Test-Retest Repeatability Study.Journal of magnetic resonance imaging : JMRI · 2021Article
- Renal Diffusion-Weighted Imaging in Healthy Dogs: Reproducibility, Test-Retest Repeatability, and Selection of the Optimal b-value Combination.Frontiers in veterinary science · 2021Article
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
purposeTo assess the correlation between each of intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) metrics in renal parenchyma with renal function, in a cohort of patients with chronic liver disease. MATERIALS AND
methodsThirty patients with liver disease underwent abdominal MRI at 1.5T, including a coronal respiratory-triggered IVIM-DWI sequence and a coronal 3D FLASH DCE-MRI acquisition. Diffusion signals in the renal cortex and medulla were fitted to the IVIM model to estimate the diffusion coefficient (D), pseudodiffusion coefficient (D*), and perfusion fraction (PF). The apparent diffusion coefficient (ADC) was calculated using all b-values. The glomerular filtration rate (GFR), cortical and medullary renal plasma flow (RPF), mean transit times (MTT) of vascular and tubular compartments and the whole kidney, were calculated from DCE-MRI data by fitting to a three-compartment model. The estimated GFR (eGFR) was calculated from serum creatinine measured 30 ± 27 days of MRI.
resultsADC, PF, and RPF were significantly higher in renal cortex vs. medulla (P < 10(-5) ). DCE-MRI GFR significantly correlated with, but underestimated, eGFR (Spearman's r/P = 0.49/0.01). IVIM-DWI parameters were not significantly correlated with eGFR. DCE-MRI GFR correlated weakly with D (cortex, r/P = 0.3/0.03; medulla r/P = 0.27/0.05) and ADC (cortex r/P = 0.28/0.04; medulla r/P = 0.34/0.01). Weak correlations were observed for pooled cortical and medullar RPF with PF (r/P = 0.32/10(-3) ) and with ADC (r/P = 0.29/0.0025). Significant negative correlations were observed for vascular MTT with cortical D* (r/P = -0.38/0.004) and D*×PF (r/P = -0.34/0.01).
conclusionThe weak correlations between renal IVIM and DCE-MRI perfusion parameters imply that these functional measures could be complementary. J. Magn. Reson. Imaging 2016;44:317-326.
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