ArticleJournal of magnetic resonance imaging : JMRI2016
Rapid T2 mapping of mouse heart using the carr-purcell-meiboom-gill sequence and compressed sensing reconstruction.
Article in Journal of magnetic resonance imaging : JMRI, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Early diagnosis of acute experimental autoimmune myocarditis in mice with preserved left ventricular ejection fraction: a feasibility study based on 9.4 T magnetic resonance.Cardiovascular diagnosis and therapy · 2026Article
- Accelerated Simultaneous TTomography (Ann Arbor, Mich.) · 2023Article
- Probing microstructural changes in muscles of leptin-deficient zebrafish by non-invasive ex-vivo magnetic resonance microimaging.PloS one · 2023Article
- Dynamic oxygen-17 MRI with adaptive temporal resolution using golden-means-based 3D radial sampling.Magnetic resonance in medicine · 2021Article
- Polydopamine-decorated tobacco mosaic virus for photoacoustic/magnetic resonance bimodal imaging and photothermal cancer therapy.Nanoscale · 2019Article
- A rapid TMagnetic resonance in medicine · 2018Article
- Article
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Authors and funding
5 authors.
Funding
Abstract
purposeTo develop and prove preliminary validation of a fast in vivo T2 mapping technique for mouse heart. MATERIALS AND
methodsMagnetic resonance imaging (MRI) experiments were performed on a 7T animal scanner. The standard Carr-Purcell-Meiboom-Gill (CPMG) sequence was modified to minimize the effect of stimulated echoes for accurate T2 quantification. The acquisition was further accelerated with the compressed sensing approach. The accuracy of the proposed method was first validated with both phantom experiments and numerical simulations. In vivo T2 measurement was performed on seven mice in a manganese-enhanced MRI study.
resultsIn phantom studies, T2 values obtained with the modified CPMG sequence are in good agreement with the standard spin-echo method (P > 0.05). Numerical simulations further demonstrated that with the application of the compressed sensing approach, fast T2 quantification with a spatial resolution of 2.3 mm can be achieved at a high temporal resolution of 1 minute per slice. With the proposed technique, an average T2 value of 25 msec was observed for mouse heart at 7T and this number decreased significantly after manganese infusion (P < 0.001).
conclusionA rapid T2 mapping technique was developed and assessed, which allows accurate T2 quantification of mouse heart at a temporal resolution of 1 minute per slice. J. Magn. Reson. Imaging 2016;44:375-382.
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