Evidence map›Paper›PMID 26854154›Full record

ArticleDiagnostics (Basel, Switzerland)2015

In Vivo Phenotyping of Tumor Metabolism in a Canine Cancer Patient with Simultaneous (18)F-FDG-PET and Hyperpolarized (13)C-Pyruvate Magnetic Resonance Spectroscopic Imaging (hyperPET): Mismatch Demonstrates that FDG may not Always Reflect the Warburg Effect.

Henrik Gutte, Adam E Hansen, Majbrit M E Larsen, Sofie Rahbek, Helle H Johannesen, Jan Ardenkjaer-Larsen, Annemarie T Kristensen, Liselotte Højgaard, Andreas Kjaer

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Hyperpolarized [1-Scientific reports · 2025
    Article
  2. [European journal of nuclear medicine and molecular imaging · 2021
    Article
  3. Review
  4. Assessment ofScientific reports · 2019
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Henrik GutteDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark. gutte@sund.ku.dk.
Adam E HansenDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark. adam.espe.hansen@regionh.dk.
Majbrit M E LarsenDepartment of Veterinary Clinical and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C 2000, Denmark. majbritt.larsen@sund.ku.dk.
Sofie RahbekDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark. sofie89falko@gmail.com.
Helle H JohannesenDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark. helle.hjorth.johannesen.01@regionh.dk.
Jan Ardenkjaer-LarsenDepartment of Electrical Engineering, Technical University of Denmark, Lyngby 2800, Denmark. JanHenrik.ArdenkjaerLarsen@ge.com.
Annemarie T KristensenDepartment of Veterinary Clinical and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C 2000, Denmark. atk@sund.ku.dk.
Liselotte HøjgaardDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark. liselotte.hoejgaard@regionh.dk.
Andreas KjaerDepartment of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark. akjaer@sund.ku.dk.
University of Copenhagen · DKTechnical University of Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this communication the mismatch between simultaneous (18)F-FDG-PET and a (13)C-lactate imaging (hyperPET) in a biopsy verified squamous cell carcinoma in the right tonsil of a canine cancer patient is shown. The results demonstrate that (18)F-FDG-PET may not always reflect the Warburg effect in all tumors.

Indexed as

13C-pyruvate18F-FDG-PETcancerdynamic nuclear polarizationhyperPEThyperpolarizedmolecular imagingMRPET/MR

Identifiers

PMID26854154
PMCPMC4665599
OpenAlexW1507394051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.