Evidence map›Paper›PMID 26854025›Full record

ArticleLeukemia2016

Deregulation of HOX genes by DNMT3A and MLL mutations converges on BMI1.

Y-T Tan, Y Sun, S-H Zhu, L Ye, C-J Zhao, W-L Zhao, Z Chen, S-J Chen, H Liu

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Leukemia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Identification and validation ofFrontiers in immunology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Y-T TanState Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital, School of Medicine and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Collaborative Innovation Center of Systems Biomedicine, Collaborative Innovation Center of Hematology, Shanghai, China.
Y SunState Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital, School of Medicine and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Collaborative Innovation Center of Systems Biomedicine, Collaborative Innovation Center of Hematology, Shanghai, China.
S-H ZhuState Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital, School of Medicine and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Collaborative Innovation Center of Systems Biomedicine, Collaborative Innovation Center of Hematology, Shanghai, China.
L YeDepartment of Medicine, Institute for Human Genetics, University of California, San Francisco, CA, USA.
C-J ZhaoState Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital, School of Medicine and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Collaborative Innovation Center of Systems Biomedicine, Collaborative Innovation Center of Hematology, Shanghai, China.
W-L ZhaoState Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital, School of Medicine and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Collaborative Innovation Center of Systems Biomedicine, Collaborative Innovation Center of Hematology, Shanghai, China.
Z ChenState Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital, School of Medicine and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Collaborative Innovation Center of Systems Biomedicine, Collaborative Innovation Center of Hematology, Shanghai, China.
S-J ChenState Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital, School of Medicine and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Collaborative Innovation Center of Systems Biomedicine, Collaborative Innovation Center of Hematology, Shanghai, China.
H LiuState Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital, School of Medicine and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Collaborative Innovation Center of Systems Biomedicine, Collaborative Innovation Center of Hematology, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell Line, TumorDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3AGene Expression Regulation, LeukemicGenes, HomeoboxHumansLeukemia, Myeloid, AcuteMiceMutationMyeloid-Lymphoid Leukemia ProteinPolycomb Repressive Complex 1DNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNMT3A protein, humanDnmt3a protein, mouseMyeloid-Lymphoid Leukemia ProteinPolycomb Repressive Complex 1

Identifiers

PMID26854025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.