ArticleScientific reports2016
Dissolved organic carbon from the upper Rio Negro protects zebrafish (Danio rerio) against ionoregulatory disturbances caused by low pH exposure.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Ionoregulatory and hematological parameters of Triportheus albus populations living in natural white- and blackwaters of the Amazon.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2026Article
- Important role of endogenous microbial symbionts of fish gills in the challenging but highly biodiverse Amazonian blackwaters.Nature communications · 2023Article
- Bacterioplankton Communities in Dissolved Organic Carbon-Rich Amazonian Black Water.Microbiology spectrum · 2023Article
- Genomic and Environmental Factors Shape the Active Gill Bacterial Community of an Amazonian Teleost Holobiont.Microbiology spectrum · 2022Article
- The direct effects of a tropical natural humic substance to three aquatic species and its influence on their sensitivity to copper.Ecotoxicology (London, England) · 2019Article
- The Use of Molecular Descriptors To Model Pharmaceutical Uptake by a Fish Primary Gill Cell Culture Epithelium.Environmental science & technology · 2019Article
- Physiological protective action of dissolved organic carbon on ion regulation and nitrogenous waste excretion of zebrafish (Danio rerio) exposed to low pH in ion-poor water.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2018Article
- The physiology of the Tambaqui (Colossoma macropomum) at pH 8.0.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2018Article
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- Influence of the natural Rio Negro water on the toxicological effects of a crude oil and its chemical dispersion to the Amazonian fish Colossoma macropomum.Environmental science and pollution research international · 2016Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The so-called "blackwaters" of the Amazonian Rio Negro are rich in highly coloured dissolved organic carbon (DOC), but ion-poor and very acidic, conditions that would cause fatal ionoregulatory failure in most fish. However these blackwaters support 8% of the world's ichthyofauna. We tested the hypothesis that native DOC provides protection against ionoregulatory dysfunction in this extreme environment. DOCs were isolated by reverse-osmosis from two Rio Negro sites. Physico-chemical characterization clearly indicated a terrigenous origin, with a high proportion of hydroxyl and phenolic sites, high chemical reactivity to protons, and unusual proteinaceous fluorescence. When tested using zebrafish (a model organism), Rio Negro DOC provided almost perfect protection against ionoregulatory disturbances associated with acute exposure to pH 4.0 in ion-poor water. DOC reduced diffusive losses of Na(+) and Cl(-), and promoted a remarkable stimulation of Na(+) uptake that otherwise would have been completely inhibited. Additionally, prior acclimation to DOC at neutral pH reduced rates of branchial Na(+) turnover, and provided similar protection against acid-induced ionoregulatory disturbances, even if the DOC was no longer present. These results reinforce the important roles that DOC molecules can play in the regulation of gill functions in freshwater fish, particularly in ion-poor, acidic blackwaters.
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