Evidence map›Paper›PMID 26852794›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2016

Unintended consequences of an 'all-clear' diagnosis for potential cancer symptoms: a nested qualitative interview study with primary care patients.

Cristina Renzi, Katriina L Whitaker, Kelly Winstanley, Susanne Cromme, Jane Wardle

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. When things go wrong: experiences of vaginal mesh complications.International urogynecology journal · 2023
    Article
  6. Review
  7. Factors influencing symptom appraisal and help-seeking of older adults with possible cancer: a mixed-methods systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2022
    Article
  8. CA125 test result, test-to-diagnosis interval, and stage in ovarian cancer at diagnosis: a retrospective cohort study using electronic health records.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021
    Article
  9. Observational
  10. Review
  11. Exploring public attitudes towards the new Faster Diagnosis Standard for cancer: a focus group study with the UK public.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019
    Article
  12. Article
  13. Disease-related factors affecting timely lymphoma diagnosis: a qualitative study exploring patient experiences.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Patient perspectives on delays in diagnosis and treatment of cancer: a qualitative analysis of free-text data.The British journal of general practice : the journal of the Royal College of General Practitioners · 2017
    Article
  19. Article
  20. Worrying about wasting GP time as a barrier to help-seeking: a community-based, qualitative study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cristina RenziHealth Behaviour Research Centre, University College London, London.
Katriina L WhitakerSchool of Health Sciences, University of Surrey, Guildford.
Kelly WinstanleyHealth Behaviour Research Centre, University College London, London.
Susanne CrommeHealth Behaviour Research Centre, University College London, London.
Jane WardleHealth Behaviour Research Centre, University College London, London.

Funding

Cancer Research UK 13276Cancer Research UK 18667Cancer Research UK C33872/A13216Cancer Research UK C48748/A16867Department of Health
6 · The paper itself

Abstract

backgroundNine out of 10 patients undergoing urgent cancer investigations receive an 'all-clear' diagnosis.

aimA qualitative approach was used to evaluate the impact of investigations that did not result in cancer diagnosis on subsequent symptom attribution and help seeking for recurrent or new possible cancer symptoms. DESIGN AND

settingA survey of symptoms, help seeking, and past investigations was sent to 4913 individuals aged ≥50 years from four UK general practices. Of 2042 responders, 62 participants were recruited still reporting at least one cancer 'alarm' symptom in a 3-month follow-up survey for a nested in-depth interview study (ensuring variation in sociodemographic characteristics).

methodFramework analysis was used to examine the in-depth semi-structured interviews and identify themes related to previous health investigations.

resultsInterviewees were on average 65 years old, and 90% reported investigations within the previous 2 years. Most often they reported gastrointestinal, urinary, and respiratory symptoms, and 42% had waited ≥3 months before help seeking. Reassurance from a previous non-cancer diagnosis explained delays in help seeking even if symptoms persisted or new symptoms developed months or years later. Others were worried about appearing hypochondriacal or that they would not be taken seriously if they returned to the doctor.

conclusionAn all-clear diagnosis can influence help seeking for months or even years in case of new or recurrent alarm symptoms. Considering the increasing number of people undergoing investigations and receiving an all-clear, it is paramount to limit unintended consequences by providing appropriate information and support. Specific issues are identified that could be addressed.

Indexed as

Primary Health CareAdultAgedAnxietyDelayed DiagnosisFemaleHealth Care SurveysHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasmsPatient Acceptance of Health CarePhysician-Patient RelationsQualitative Researchcancerdelaydiagnosisdiagnostic investigationshelp seekingsymptoms

Identifiers

PMID26852794
PMCPMC4758495

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.