ArticleEuropean radiology2016
Differentiation of myocardial ischemia and infarction assessed by dynamic computed tomography perfusion imaging and comparison with cardiac magnetic resonance and single-photon emission computed tomography.
Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed, 52 citations in OpenAlex.
- Protocol optimization and myocardial blood flow quantification in dynamic myocardial perfusion CT-where do we stand?European radiology · 2025Article
- Preliminary experience with dynamic CT myocardial perfusion imaging: a single-centre perspective.Polish journal of radiology · 2025Article
- Imaging biomarkers in cardiac CT: moving beyond simple coronary anatomical assessment.La Radiologia medica · 2024Review
- Diagnostic value of computed tomography myocardial perfusion imaging to detect coexisting microvascular dysfunction in patients with obstructive epicardial coronary artery disease.Quantitative imaging in medicine and surgery · 2023Article
- Dynamic CT Myocardial Perfusion: The Role of Functional Evaluation in the Diagnosis of Coronary Artery Disease.Journal of clinical medicine · 2023Review
- Dynamic Perfusion Computed Tomography for the Assessment of Concomitant Coronary Artery Disease in Patients with a History of Percutaneous Transluminal Angioplasty for Chronic Limb-Threatening Ischemia-A Pilot Study.Journal of cardiovascular development and disease · 2023Article
- Dynamic myocardial CT perfusion imaging-state of the art.European radiology · 2023Review
- A Novel CT Perfusion-Based Fractional Flow Reserve Algorithm for Detecting Coronary Artery Disease.Journal of clinical medicine · 2023Article
- Feasibility of four-dimensional similarity filter for radiation dose reduction in dynamic myocardial computed tomography perfusion imaging.Frontiers in radiology · 2023Article
- A Novel Quantitative Parameter for Static Myocardial Computed Tomography: Myocardial Perfusion Ratio to the Aorta.Journal of clinical medicine · 2022Article
- [Beyond Coronary CT Angiography: CT Fractional Flow Reserve and Perfusion].Taehan Yongsang Uihakhoe chi · 2022Review
- Association between coronary plaque volume and myocardial ischemia detected by dynamic perfusion CT imaging.Frontiers in cardiovascular medicine · 2022Article
- Myocardial perfusion assessment in the infarct core and penumbra zones in an in-vivo porcine model of the acute, sub-acute, and chronic infarction.European radiology · 2021Article
- New transluminal attenuation gradient derived from dynamic coronary CT angiography: diagnostic ability of ischemia detected byHeart and vessels · 2021Article
- A non-invasive nanoparticles for multimodal imaging of ischemic myocardium in rats.Journal of nanobiotechnology · 2021Article
- Coronary artery stenosis-related perfusion ratio using dynamic computed tomography myocardial perfusion imaging: a pilot for identification of hemodynamically significant coronary artery disease.Cardiovascular intervention and therapeutics · 2020Observational
- Clinical application of four-dimensional noise reduction filtering with a similarity algorithm in dynamic myocardial computed tomography perfusion imaging.The international journal of cardiovascular imaging · 2020Observational
- Computed tomographic evaluation of myocardial ischemia.Japanese journal of radiology · 2020Review
- Hemispherical photoacoustic imaging of myocardial infarction: in vivo detection and monitoring.European radiology · 2018Article
- Myocardial Assessment with Cardiac CT: Ischemic Heart Disease and Beyond.Current cardiovascular imaging reports · 2018Review
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the feasibility of myocardial blood flow (MBF) by computed tomography from dynamic CT perfusion (CTP) for detecting myocardial ischemia and infarction assessed by cardiac magnetic resonance (CMR) or single-photon emission computed tomography (SPECT).
methodsFifty-three patients who underwent stress dynamic CTP and either SPECT (n = 25) or CMR (n = 28) were retrospectively selected. Normal and abnormal perfused myocardium (ischemia/infarction) were assessed by SPECT/CMR using 16-segment model. Sensitivity and specificity of CT-MBF (mL/g/min) for detecting the ischemic/infarction and severe infarction were assessed.
resultsThe abnormal perfused myocardium and severe infarction were seen in SPECT (n = 90 and n = 19 of 400 segments) and CMR (n = 223 and n = 36 of 448 segments). For detecting the abnormal perfused myocardium, sensitivity and specificity were 80 % (95 %CI, 71-90) and 86 % (95 %CI, 76-91) in SPECT (cut-off MBF, 1.23), and 82 % (95 %CI, 76-88) and 87 % (95 %CI, 80-92) in CMR (cut-off MBF, 1.25). For detecting severe infarction, sensitivity and specificity were 95 % (95 %CI, 52-100) and 72 % (95 %CI, 53-91) in SPECT (cut-off MBF, 0.92), and 78 % (95 %CI, 67-97) and 80 % (95 %CI, 58-86) in CMR (cut-off MBF, 0.98), respectively.
conclusionsDynamic CTP has a potential to detect abnormal perfused myocardium and severe infarction assessed by SPECT/CMR using comparable cut-off MBF. KEY POINTS: • CT-MBF accurately reflects the severity of myocardial perfusion abnormality. • CT-MBF provides good diagnostic accuracy for detecting myocardial perfusion abnormalities. • CT-MBF may assist in stratifying severe myocardial infarction in abnormal perfusion myocardium.
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