Evidence map›Paper›PMID 26851543›Full record

ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2016

Hepatitis B virus infection among pregnant women in Haiti: A cross-sectional serosurvey.

Rania A Tohme, Jocelyne Andre-Alboth, Alexandra Tejada-Strop, Ran Shi, Jacques Boncy, Jeannot François, Jean Wysler Domercant, Mark Griswold, Erlantz Hyppolite, Paul Adrien and 1 more

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In one paragraph

Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Incidence of Etiology-specific Hepatocellular Carcinoma: Diverging Trends and Significant Heterogeneity by Race and Ethnicity.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
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  6. Observational
  7. Article
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  12. Article
  13. Prevalence of Chronic Hepatitis B Virus Infection among Children in Haiti, 2017.The American journal of tropical medicine and hygiene · 2019
    Article
  14. Seroprevalence of Hepatitis A and Hepatitis E Viruses among Pregnant Women in Haiti.The American journal of tropical medicine and hygiene · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Rania A TohmeUS Centers for Disease Control and Prevention, Atlanta, GA,USA. Electronic address: rtohme@cdc.gov.
Jocelyne Andre-AlbothNational Public Health Laboratory, Ministry of Public Health and Population, Haiti.
Alexandra Tejada-StropUS Centers for Disease Control and Prevention, Atlanta, GA,USA.
Ran ShiEmory University, Atlanta, GA, USA.
Jacques BoncyNational Public Health Laboratory, Ministry of Public Health and Population, Haiti.
Jeannot FrançoisExpanded Program of Immunization, Ministry of Public Health and Population, Port-au-Prince, Haiti.
Jean Wysler DomercantHaiti Country Office, Centers for Disease Control and Prevention, Port-au-Prince, Haiti.
Mark GriswoldGlobal Program, National Alliance of State and Territorial AIDS Directors, Washington DC, USA.
Erlantz HyppoliteNational Alliance of State and Territorial AIDS Directors, Port-au-Prince, Haiti.
Paul AdrienDirectorate of Epidemiology, Laboratory and Research, Ministry of Public Health and Population, Port-au-Prince, Haiti.
Saleem KamiliUS Centers for Disease Control and Prevention, Atlanta, GA,USA.
Centers for Disease Control and Prevention · USNational Public Health Laboratory · NPEmory University · USNational Alliance of State and Territorial AIDS Directors · USUniversity of Haiti · HT

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundHepatitis B vaccine administered shortly after birth is highly effective in preventing mother to child transmission (MTCT) of infection. While hepatitis B vaccine was introduced in Haiti as part of a combined pentavalent vaccine in 2012, a birth dose is not yet included in the immunization schedule.

objectivesDetermine the seroprevalence of hepatitis B virus (HBV) infection among pregnant women to evaluate the risk of MTCT. STUDY

designWe selected 1364 residual serum specimens collected during a 2012 human immunodeficiency virus (HIV) sentinel serosurvey among pregnant women attending antenatal care clinics. Haiti was stratified into two regions: West, which includes metropolitan Port-au-Prince, and non-West, which includes all other departments. We evaluated the association between demographic and socioeconomic characteristics and HIV infection with HBV infection.

resultsOf 1364 selected specimens, 1307 (96%) were available for testing. A total of 422 specimens (32.7%) tested positive for total anti-HBc (38.2% in West vs. 27% in non-West, p<0.001), and 33 specimens (2.5%) were HBsAg positive (2.1% in West vs. 3% in non-West, p=0.4). Of HBsAg positive specimens, 79% had detectable HBV DNA. Women aged 30 and older had more than double the odds of positive total anti-HBc than women aged 15-19 years (p<0.001). Women with secondary (adjusted odds ratio (aOR)=0.54; 95% CI: 0.36-0.81) and post-secondary education (aOR=0.40, 95% CI: 0.19-0.79) had lower odds of total anti-HBc positivity compared with women with no education. HIV-status was not associated with HBV infection.

conclusionsHaiti has an intermediate endemicity of chronic HBV infection with high prevalence of positive HBV DNA among chronically infected women. Introduction of a universal birth dose of hepatitis B vaccine might help prevent perinatal HBV transmission.

Indexed as

AdolescentAdultCross-Sectional StudiesDNA, ViralFemaleHaitiHepatitis BHepatitis B AntibodiesHepatitis B, ChronicHepatitis B Surface AntigensHepatitis B VaccinesHIV InfectionsHumansInfectious Disease Transmission, VerticalMiddle AgedPregnancyDNA, ViralHepatitis B AntibodiesHepatitis B Surface AntigensHepatitis B VaccinesHaitiHepatitis BHepatitis B vaccinesPregnant womenSerosurvey

Identifiers

PMID26851543
PMCPMC5802338
OpenAlexW2256804921

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.