ArticleCancer discovery2016
Adenoid Cystic Carcinoma Can Be Driven by MYB or MYBL1 Rearrangements: New Insights into MYB and Tumor Biology.
Article in Cancer discovery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 27 citations in OpenAlex.
- Adenoid cystic carcinoma: insights from molecular characterization and therapeutic advances.MedComm · 2024Review
- High-risk subtype: Clinical manifestations and molecular characteristics of submandibular gland adenoid cystic carcinoma.Frontiers in oncology · 2022Article
- Establishment of patient-derived xenograft models of adenoid cystic carcinoma to assess pre-clinical efficacy of combination therapy of a PI3K inhibitor and retinoic acid.American journal of cancer research · 2021Article
- First-in-human phase I clinical trial of a combined immune modulatory approach using TetMYB vaccine and Anti-PD-1 antibody in patients with advanced solid cancer including colorectal or adenoid cystic carcinoma: The MYPHISMO study protocol (NCT03287427).Contemporary clinical trials communications · 2019Article
- Notch1 signaling in NOTCH1-mutated mantle cell lymphoma depends on Delta-Like ligand 4 and is a potential target for specific antibody therapy.Journal of experimental & clinical cancer research : CR · 2019Article
- Identification and Characterization of a Novel Protein ASP-3 Purified fromMarine drugs · 2019Article
- c-MYB and DMTF1 in Cancer.Cancer investigation · 2019Review
- The MYB/miR-130a/NDRG2 axis modulates tumor proliferation and metastatic potential in salivary adenoid cystic carcinoma.Cell death & disease · 2018Article
- Mut2Vec: distributed representation of cancerous mutations.BMC medical genomics · 2018Article
- Personalized oncogenomic analysis of metastatic adenoid cystic carcinoma: using whole-genome sequencing to inform clinical decision-making.Cold Spring Harbor molecular case studies · 2018Article
- Article
- Identification of potential transcriptomic markers in developing pediatric sepsis: a weighted gene co-expression network analysis and a case-control validation study.Journal of translational medicine · 2017Article
- A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.Cell reports · 2017Article
- The Spectrum of Triple-Negative Breast Disease: High- and Low-Grade Lesions.The American journal of pathology · 2017Review
- Genetic analysis of microglandular adenosis and acinic cell carcinomas of the breast provides evidence for the existence of a low-grade triple-negative breast neoplasia family.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2017Article
- Genomic and transcriptomic heterogeneity in metaplastic carcinomas of the breast.NPJ breast cancer · 2017Article
- Triple-negative breast cancer: the importance of molecular and histologic subtyping, and recognition of low-grade variants.NPJ breast cancer · 2016Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A majority of adenoid cystic carcinomas (AdCC)-rare tumors of the salivary gland and some other organs-have recently been found to be driven by chromosomal translocations resulting in MYB-NFIB fusions. Brayer and colleagues and Mitani and colleagues have now reported that AdCCs can alternatively be driven by similar rearrangements involving a second MYB family gene, MYBL1, and that these two drivers act in remarkably similar ways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.